Actively Recruiting

Phase Not Applicable
Age: 18Years - 52Years
FEMALE
Healthy Volunteers
NCT05224726

Platelet Rich Plasma for Uterine Scar

Led by The University of Texas Health Science Center, Houston · Updated on 2025-08-26

40

Participants Needed

1

Research Sites

154 weeks

Total Duration

On this page

Sponsors

T

The University of Texas Health Science Center, Houston

Lead Sponsor

S

Sheba Medical Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

When vessel wall injury occurs, platelets become activated, releasing more than 30 bioactive proteins, many of which have a fundamental role in hemostasis, inflammation and ultimate wound healing. Platelet-rich plasma (PRP), a modification of fibrin glue made from autologous blood, is being used to deliver growth factors in high concentration to sites requiring wound healing. PRP is obtained from a sample of patients' blood drawn at the time of treatment. As the rate of cesarean deliveries has been rising, long-term adverse sequelae due to uterine scar defects have been increasing. PRP might be a simple preventive treatment that potentially can reduce morbidity following cesarean deliveries.

CONDITIONS

Official Title

Platelet Rich Plasma for Uterine Scar

Who Can Participate

Age: 18Years - 52Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Women undergoing elective cesarean delivery
  • Term pregnancy (≥37 weeks of gestation)
Not Eligible

You will not qualify if you...

  • Thrombocytopenia (platelet count below 70,000)
  • Connective tissue disease
  • Uterine scars other than cesarean (such as after myomectomy or cornual resection)
  • Malformed uterus (unicornuate, bicornuate, didelphic)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sheba Medical Center

Ramat Gan, Center, Israel, 55030

Actively Recruiting

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Research Team

A

Aya A Mohr-Sasson, M.D

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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