Actively Recruiting
Platelet Serotonin Deficiencies: the Strasbourg Experience
Led by University Hospital, Strasbourg, France · Updated on 2025-12-24
50
Participants Needed
1
Research Sites
61 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Hemorrhagic syndromes are investigated using algorithms established by reference centers and hemostasis societies. The investigation of platelet dense granules (nucleotide and serotonin testing) is part of the second-line tests. It can be performed in cases of platelet aggregation abnormalities in platelet-rich plasma (PRP) suggesting a secretion abnormality, or in cases where the latter is normal, it can be performed if the patient's clinical presentation points to a primary hemostasis abnormality and the clinician wishes to pursue further investigations Intraplatelet serotonin deficiencies are often iatrogenic and may be accompanied by bleeding. Their impact on platelet function is poorly documented.
CONDITIONS
Official Title
Platelet Serotonin Deficiencies: the Strasbourg Experience
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patient (≥ 18 years old)
- Treated at Strasbourg University Hospital for a hemorrhagic syndrome suggesting a primary hemostasis abnormality with normal von Willebrand factor
- Treatment period from January 1, 2023, to April 1, 2024
You will not qualify if you...
- Refusal to participate in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Centre de Ressources et de Compétences des Maladies Hémorragiques Constitutionnelles - CHU de Strasbourg - France
Strasbourg, France, 67091
Actively Recruiting
Research Team
D
Dominique DESPREZ, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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