Actively Recruiting

Phase 2
Phase 3
Age: 13Years - 50Years
All Genders
Healthy Volunteers
NCT06519955

Can PLIA Reduce Early Post-operative Pain After PAO Surgery?

Led by Michael C Willey · Updated on 2026-04-17

120

Participants Needed

1

Research Sites

99 weeks

Total Duration

On this page

Sponsors

M

Michael C Willey

Lead Sponsor

N

Northwestern University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to compare different peri-incisional local infiltrative anesthesia (PLIA) methods in patients ages 13 to 50 undergoing a periacetabular osteotomy (PAO). The main questions to answer here are: 1. Does PLIA impact post-operative pain after PAO? 2. Does PLIA impact pain medication usage as measured by morphine equivalent dosing (MED) after PAO? 3. Does the timing of PLIA administration impact post-operative pain and MED after PAO? Participants will be asked to complete some surveys; demographics survey, General Self-Efficacy Scale (GSE) and the Pain Resilience Scale. All other information will be gathered from the patients medical chart. Researchers will compare three groups. 1.) Patients who do not receive PLIA. 2.) Patients who receive PLIA after their incision is closed. 3.) Patients who receive PLIA throughout PAO.

CONDITIONS

Official Title

Can PLIA Reduce Early Post-operative Pain After PAO Surgery?

Who Can Participate

Age: 13Years - 50Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adolescent or young adult diagnosed with hip dysplasia indicated for PAO at University of Iowa Hospital and Clinics.
Not Eligible

You will not qualify if you...

  • Unable to provide informed consent.
  • Pregnant or breast-feeding individuals
  • Prisoner or ward of the state
  • Allergy or medical contradiction to any of the study medications
  • Patients undergoing femoral osteotomy or surgical hip dislocation with PAO will be excluded

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Iowa Health Care

Iowa City, Iowa, United States, 52242

Actively Recruiting

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Research Team

A

Ashley S Kochuyt

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

3

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