Actively Recruiting
Association Between Pneumoperitoneum Duration and Changes in Serum Bicarbonate Levels in Patients Undergoing Laparoscopic Inguinal Hernia Repair: A Prospective Observational Study
Led by Haseki Training and Research Hospital · Updated on 2026-03-16
100
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This observational study investigates how the length of pneumoperitoneum during laparoscopic inguinal hernia surgery affects changes in blood bicarbonate levels. Pneumoperitoneum involves using carbon dioxide gas to create space inside the abdomen for surgery. The study aims to understand if longer pneumoperitoneum times are linked to shifts in blood bicarbonate after surgery, which may improve knowledge of metabolic changes during laparoscopic procedures. Adults scheduled for elective laparoscopic inguinal hernia repair using the transabdominal preperitoneal (TAPP) technique will participate. Blood gas values, including bicarbonate, pH, and partial pressure of carbon dioxide (pCO2), will be measured before surgery and again two hours after surgery. The duration of pneumoperitoneum during the operation will be recorded and analyzed alongside these blood gas changes. Secondary measures include postoperative pain scores and early complications within 24 hours. Participants will undergo blood sampling before and two hours post-surgery to assess changes in serum bicarbonate and other acid-base balance parameters. Researchers will compare these changes with pneumoperitoneum duration to evaluate their relationship. The study will monitor pain and any early postoperative complications. Total participant involvement covers the surgery day and the immediate 24-hour postoperative period, enhancing understanding of metabolic effects during laparoscopic hernia repair.
CONDITIONS
Brief Title
Pneumoperitoneum Duration and Bicarbonate Changes in Laparoscopic Hernia Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 6518 years
- Patients undergoing laparoscopic inguinal hernia repair using the TAPP technique
- Ability to provide informed consent
You will not qualify if you...
- Pregnancy
- Severe cardiovascular disease
- Renal insufficiency
- Patients requiring additional intra-abdominal surgical procedures
- Strangulated inguinal hernia requiring bowel resection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for eligibility assessment
Duration - Surgery day plus 2 hours post-operation
Participants undergo laparoscopic inguinal hernia repair using the TAPP technique as part of routine clinical care. Pneumoperitoneum duration during surgery is recorded, and blood gas measurements are obtained before surgery and at the second postoperative hour to assess serum bicarbonate and other acid-base parameters.
1 surgical procedure visit and 1 postoperative visit approximately 2 hours after surgery
Duration - Up to 24 hours after surgery
Participants are monitored for postoperative pain and early complications within the first 24 hours after surgery.
Approximately 1 follow-up visit within 24 hours post-surgery
Trial Site Locations
Total: 1 location
1
Haseki Training and Research Hospital
Istanbul, Turkey (Türkiye), 34265
Actively Recruiting
Research Team
O
Osman Sibic, MD
B
Bahar Canbay Torun, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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