Actively Recruiting

Age: 0Months - 12Months
All Genders
NCT06425107

Point-of-Care Lung Ultrasound for Prognosis in Critically Ill Infants With Acute Lower Respiratory Tract Infection

Led by Vittore Buzzi Children's Hospital · Updated on 2024-05-22

100

Participants Needed

1

Research Sites

78 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Prospective, observational multicentric study which aims at identifying lung POCUS (Point of Care UltraSound) findings associated with failure of noninvasive ICU-LRS (Intensive Care Unit Level Respiratory Support) (defined as escalation of settings or need for intubation and invasive mechanical ventilation) in infants requiring noninvasive ICU-LRS in the ICU for bronchiolitis and other LRTI (Low Respiratory Tract Infection) and at identifying lung, pleural, and diaphragm POCUS findings that are associated with a clinical improvement after escalation of ICU-LRS support by comparing POCUS findings from the first 24 hours of ICU stay to a subsequent study 1 day later.

CONDITIONS

Official Title

Point-of-Care Lung Ultrasound for Prognosis in Critically Ill Infants With Acute Lower Respiratory Tract Infection

Who Can Participate

Age: 0Months - 12Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age under 1 year at hospital admission
  • Admission to the Pediatric Intensive Care Unit (PICU) for suspected or confirmed lower respiratory tract infection
  • Receiving noninvasive intensive care respiratory support (HFNC >1L/kg/min, negative pressure, or noninvasive positive pressure ventilation such as CPAP, BiPAP, or NIMV) within the first 12 hours of ICU stay
Not Eligible

You will not qualify if you...

  • Use of invasive ventilation via endotracheal tube or tracheostomy as initial support or within the first 12 hours of ICU stay
  • Presence of only upper respiratory symptoms such as stridor or stertor
  • Corrected gestational age less than 37 weeks at ICU admission
  • Use of intensive care respiratory support solely for nonrespiratory reasons (e.g., shock) or pulmonary edema due only to noninfectious causes
  • Prior participation in this study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Vittore Buzzi Children's Hospital

Milan, Italy, 20154

Actively Recruiting

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Research Team

A

Anna Camporesi, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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