Actively Recruiting

Phase 2
Age: 70Years +
All Genders
NCT06176729

Pola-R2 in Newly Diagnosed Non-fit Elderly DLBCL Patients

Led by Yan Zhang, MD · Updated on 2023-12-20

30

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

Sponsors

Y

Yan Zhang, MD

Lead Sponsor

P

Peking University Third Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a prospective, single-arm, phase II study, and the purpose of this study is to evaluate the efficacy and safety of Pola-R2 regimen in newly diagnosed elderly diffuse large B cell lymphoma classified into un-fit or frail group by comprehensive geriatric assessment(CGA).

CONDITIONS

Official Title

Pola-R2 in Newly Diagnosed Non-fit Elderly DLBCL Patients

Who Can Participate

Age: 70Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient volunteered and signed informed consent
  • Histopathologically confirmed diffuse large B cell lymphoma (DLBCL) and treatment naive (except corticosteroids alone)
  • Age 70 years or older and classified as un-fit or frail by comprehensive geriatric assessment
  • Adequate organ function and bone marrow reserve
Not Eligible

You will not qualify if you...

  • Having another active malignancy besides lymphoma
  • Active hepatitis B virus (HBV) infection
  • Unstable systemic disease including active infection (other than local), severe cardiac, liver, kidney, or metabolic disease requiring therapy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China, 100730

Actively Recruiting

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Research Team

W

Wei Wang, MD

CONTACT

Z

Zhaohui Zhu, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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