Actively Recruiting

Age: 18Years +
All Genders
NCT07196397

POLish Registry of CArdioneuroablation and CArdioneuromodulation

Led by SABAMED Medical Center Ltd. · Updated on 2025-09-29

1000

Participants Needed

1

Research Sites

370 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The multicentre observational study POL-CA involves a wide spectrum of patients with a history of syncopy. The study recruits patients with diagnosed vasovagal syndrome, cardioinhibitory carotid sinus syndrome, symptomatic sinus bradycardia or atrioventricular block, postural orthostatic tachycardia syndrome, orthostatic hypotension, and inappropriate sinus tachycardia syndrome. This is an observational, controlled study with retrospective, clinical data analysis of previously treated patients and the analysis of syncopal patients prospectively recruited into the study. The aim of the POL-CA registry is to create a platform for physicians to record treatment data for patients undergoing procedures that affect innervation or modify cardiovascular reflexes (cardioneuroablation, cardioneuromodulation) in order to provide a multicentre summary of population characteristics and treatment outcomes based on a standardized POL-CA questionnaire and methodology for various arrhythmias.

CONDITIONS

Official Title

POLish Registry of CArdioneuroablation and CArdioneuromodulation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 218 years
  • Diagnosis of at least one of the following: inappropriate sinus tachycardia, postural orthostatic tachycardia syndrome, vasovagal syncope, cardioinhibitory carotid sinus syndrome, symptomatic sinus bradycardia or functional AV block, orthostatic hypotension
  • History of recurrent autonomic symptoms such as syncope, bradycardia, palpitations, or orthostatic intolerance
  • Undergoing or previously underwent interventional treatment affecting cardiac autonomic innervation, including cardioneuroablation, SN-sparing ablation, or cardiac sympathetic denervation
  • Provided written informed consent for prospective participation
Not Eligible

You will not qualify if you...

  • Structural heart disease requiring surgical intervention
  • Permanent pacemaker or implantable cardioverter defibrillator (ICD) implanted prior to enrollment
  • Inability to complete follow-up assessments or questionnaires
  • Severe psychiatric conditions impairing participation
  • Participation in another interventional clinical trial

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

SabaMed

Rzeszów, Poland

Actively Recruiting

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Research Team

S

Sebastian Stec, Prof., MD, PhD

CONTACT

M

Marta Kornaszewska, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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