Actively Recruiting
Pollution Intervention to Impact Kids Asthma Study
Led by University of Pittsburgh · Updated on 2026-02-27
351
Participants Needed
1
Research Sites
201 weeks
Total Duration
On this page
Sponsors
U
University of Pittsburgh
Lead Sponsor
N
National Institute of Environmental Health Sciences (NIEHS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children. It will also learn about children with asthma who report being more sensitive to outdoor air pollution. The main questions it aims to answer are: * Does adding either information about the EPA-AQI or commercial AQI improve asthma outcomes over time? * Are there changes in nasal gene expression in children with asthma who report they are more sensitive to outdoor air pollution? Researchers will compare EPA-AQI and the commercial-AQI groups to a control group to either AQI works to improve asthma. Participants will: * Receive standardized outdoor air pollution education and an asthma action plan * Provide nose and blood specimens * Have visits every 4 weeks for 48 weeks, 10 will be conducted by telephone calls and 3 visits will be in person.
CONDITIONS
Official Title
Pollution Intervention to Impact Kids Asthma Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- A healthcare provider diagnosis of persistent asthma (Steps 2-5 as defined by US guidelines) or intermittent asthma (Step 1) plus at least one severe asthma exacerbation requiring systemic steroids or emergency care in the prior 12 months
- Home access to a smartphone or internet
- Primary residence in Allegheny County, Pennsylvania
- Only one participant per household
- Age between 8 and 17 years
- Healthcare provider evaluation for asthma within the prior year
You will not qualify if you...
- Diagnosis of other active chronic respiratory diseases such as cystic fibrosis or bronchopulmonary dysplasia
- Neuromuscular disorders
- Chronic disorders limiting independent movement, such as spastic quadriplegia
- Cyanotic heart disease
- Plans to move away from Allegheny County, Pennsylvania within the next 12 months
- Use of intranasal or oral/intramuscular/intravenous corticosteroids within 4 weeks before randomization
- Current participation in another asthma intervention trial
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UPMC Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15224
Actively Recruiting
Research Team
P
Pediatric Asthma Center
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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