Actively Recruiting
Polymer Induced Liquid Precursor (PILP) in Adults in With Dentin Caries
Led by University of California, San Francisco · Updated on 2026-03-06
30
Participants Needed
1
Research Sites
99 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if polymer-induced liquid precursor (PILP) can be used safely to treat dentin caries (cavities) in adults. The main question it aims to answer is: Is PILP (conditioner or liner) safe in adult teeth with dental caries? Researchers will compare PILP to a placebo (a look-alike substance that contains no drug) to see if PILP safely treats cavities in teeth. Participants will: 1) Have PILP or placebo applied to their tooth prior to the placement of a filling in the tooth, 2) Complete two telephone calls within three months of filling placement and 3) Visit the clinic at three months and six months after the placement of the filling.
CONDITIONS
Official Title
Polymer Induced Liquid Precursor (PILP) in Adults in With Dentin Caries
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Willing to follow all study procedures and be available throughout the study
- Male or female aged 18 to 64 years
- In good general health (ASA class 1 or 2)
- Have at least one posterior tooth with dentin caries
- Tooth must have healthy pulp with no irreversible pulpitis or periapical radiolucency
- Tooth should have no existing restorations
- Caries should be a single surface Class I or Class V lesion
- Tooth planned for intra-coronal restoration (composite or resin-modified glass ionomer)
- Restoration needed based on ICDAS assessment
You will not qualify if you...
- Known allergic reactions to any components of the study devices
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of California San Francisco, School of Dentistry
San Francisco, California, United States, 94143
Actively Recruiting
Research Team
J
Jean Star, DDS, MPH
CONTACT
J
Jessica Snider, MBA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here