Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05136222

Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease

Led by University of Melbourne · Updated on 2022-06-23

244

Participants Needed

13

Research Sites

323 weeks

Total Duration

On this page

Sponsors

U

University of Melbourne

Lead Sponsor

A

Austin Hospital, Melbourne Australia

Collaborating Sponsor

AI-Summary

What this Trial Is About

A two-arm, individual participant randomised controlled, assessor-blinded trial in 7 MND care centres across Australia will be undertaken.

CONDITIONS

Official Title

Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age >18 years
  • Clinical indication to commence long term NIV
  • Confirmed clinical diagnosis of underlying condition
Not Eligible

You will not qualify if you...

  • Medically unstable
  • Hypoventilation due to sedative or respiratory depressant medications
  • Use of NIV for more than 1 month in the previous 3 months
  • Inability to provide informed consent
  • Previous intolerance of NIV

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 13 locations

1

Flinders Medical Centre

Adelaide, Australia

Not Yet Recruiting

2

The Prince Charles Hospital

Brisbane, Australia

Not Yet Recruiting

3

Motor Neurone Disease Australia

Canberra, Australia

Not Yet Recruiting

4

Austin Health

Melbourne, Australia

Actively Recruiting

5

Australian MND Registry

Melbourne, Australia

Not Yet Recruiting

6

FightMND

Melbourne, Australia

Not Yet Recruiting

7

Institute for Breathing and Sleep

Melbourne, Australia

Not Yet Recruiting

8

Monash University

Melbourne, Australia

Not Yet Recruiting

9

University of Melbourne

Melbourne, Australia

Not Yet Recruiting

10

Sir Charles Gairdner Hospital

Perth, Australia

Not Yet Recruiting

11

Macquarie University

Sydney, Australia

Not Yet Recruiting

12

Royal Prince Alfred Hospital

Sydney, Australia

Not Yet Recruiting

13

Westmead Hospital

Sydney, Australia

Not Yet Recruiting

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Research Team

D

David Berlowitz, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease | DecenTrialz