Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07535060

Pontic Site Development With or Without Fixed Partial Denture

Led by Cairo University · Updated on 2026-05-01

20

Participants Needed

1

Research Sites

86 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the effectiveness of soft tissue augmentation using connective tissue graft (CTG) in pontic site defects. It compares clinical and volumetric outcomes between sites with an existing fixed partial denture (FDP) and sites without an FDP. Following tooth extraction, alveolar ridge resorption often leads to soft tissue defects that can compromise esthetics, function, and prosthetic outcomes. CTG is considered the gold standard for soft tissue augmentation due to its predictable improvement in tissue thickness and stability. In this non-randomized clinical trial, patients with single edentulous sites in the esthetic zone will undergo CTG using a standardized surgical technique. The primary outcome is keratinized tissue thickness, while secondary outcomes include keratinized tissue width, volumetric soft tissue changes, esthetic evaluation (Pink Esthetic Score), plaque index, post-operative pain, and patient satisfaction. Clinical and digital assessments will be conducted preoperatively and at follow-up intervals up to 6 months. The study aims to determine whether performing CTG around an existing bridge provides comparable or improved outcomes compared to sites without a bridge, potentially offering a less invasive alternative to prosthetic replacement.

CONDITIONS

Official Title

Pontic Site Development With or Without Fixed Partial Denture

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with a missing tooth in the esthetic zone (2nd premolar to 2nd premolar), missing for at least 3 months, with or without fixed partial denture
  • Systemically healthy patients
  • 18 years of age or older
  • Intact gum tissue with at least 2mm keratinized tissue on adjacent teeth
  • Patients willing to provide informed consent
Not Eligible

You will not qualify if you...

  • Current smokers
  • Pregnant or breastfeeding women
  • Patients with periodontitis
  • Patients with a severe gagging reflex
  • Handicapped or mentally challenged patients
  • Patients with active soft tissue infections

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Faculty of Dentistry, Cairo University

Cairo, Egypt, 12613

Actively Recruiting

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Research Team

A

Ahmed Mohamed Elatreby, BDs

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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