Actively Recruiting
Pontic Site Development With or Without Fixed Partial Denture
Led by Cairo University · Updated on 2026-05-01
20
Participants Needed
1
Research Sites
86 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to evaluate the effectiveness of soft tissue augmentation using connective tissue graft (CTG) in pontic site defects. It compares clinical and volumetric outcomes between sites with an existing fixed partial denture (FDP) and sites without an FDP. Following tooth extraction, alveolar ridge resorption often leads to soft tissue defects that can compromise esthetics, function, and prosthetic outcomes. CTG is considered the gold standard for soft tissue augmentation due to its predictable improvement in tissue thickness and stability. In this non-randomized clinical trial, patients with single edentulous sites in the esthetic zone will undergo CTG using a standardized surgical technique. The primary outcome is keratinized tissue thickness, while secondary outcomes include keratinized tissue width, volumetric soft tissue changes, esthetic evaluation (Pink Esthetic Score), plaque index, post-operative pain, and patient satisfaction. Clinical and digital assessments will be conducted preoperatively and at follow-up intervals up to 6 months. The study aims to determine whether performing CTG around an existing bridge provides comparable or improved outcomes compared to sites without a bridge, potentially offering a less invasive alternative to prosthetic replacement.
CONDITIONS
Official Title
Pontic Site Development With or Without Fixed Partial Denture
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with a missing tooth in the esthetic zone (2nd premolar to 2nd premolar), missing for at least 3 months, with or without fixed partial denture
- Systemically healthy patients
- 18 years of age or older
- Intact gum tissue with at least 2mm keratinized tissue on adjacent teeth
- Patients willing to provide informed consent
You will not qualify if you...
- Current smokers
- Pregnant or breastfeeding women
- Patients with periodontitis
- Patients with a severe gagging reflex
- Handicapped or mentally challenged patients
- Patients with active soft tissue infections
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Faculty of Dentistry, Cairo University
Cairo, Egypt, 12613
Actively Recruiting
Research Team
A
Ahmed Mohamed Elatreby, BDs
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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