Actively Recruiting
Clinical and Volumetric Evaluation of Soft Tissue Augmentation Using Connective Tissue Graft in Pontic Site Defects With and Without Fixed Partial Dentures
Led by Cairo University · Updated on 2026-05-01
20
Participants Needed
1
Research Sites
N/A
Total Duration
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AI-Summary
What this Trial Is About
Researchers are evaluating soft tissue augmentation using a connective tissue graft (CTG) in patients with pontic site defects, focusing on sites with and without an existing fixed partial denture (FDP). The study investigates whether performing CTG around an existing bridge can provide similar or improved clinical and volumetric outcomes compared to sites without a bridge. The goal is to address alveolar ridge resorption after tooth extraction, which often causes soft tissue problems affecting esthetics and function. Participants will undergo a standardized surgical procedure involving CTG harvested from the palate and placed at the pontic site using a minimally invasive pouch technique. The study compares two groups: those with pontic site defects and an existing FDP where the prosthesis remains during augmentation, and those without an FDP who will receive a temporary bridge during healing. All procedures occur under controlled clinical conditions with initial periodontal preparation. During the study, patients will have clinical and digital assessments before surgery and at follow-ups up to six months. Measurements include keratinized tissue thickness and width, volumetric soft tissue changes, esthetic scores, plaque index, post-operative pain, and patient satisfaction. Monitoring aims to evaluate healing, tissue stability, and esthetic results, supporting a less invasive treatment approach that may reduce discomfort and treatment time.
CONDITIONS
Brief Title
Pontic Site Development With or Without Fixed Partial Denture
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with a missing tooth in the esthetic zone (from 2nd premolar to 2nd premolar), missing for at least 3 months, with or without fixed partial denture
- Systemically healthy patients
- Age 18 years or older
- Intact gum tissue with at least 2mm of keratinized tissue on adjacent teeth
- Willingness to provide informed consent
You will not qualify if you...
- Smokers
- Pregnant or breastfeeding women
- Patients with periodontitis
- Severe gagging reflex
- Handicapped or mentally challenged patients
- Active soft tissue infection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single surgical procedure with post-operative care over 2 weeks
Participants receive soft tissue augmentation using a connective tissue graft (CTG) placed at the pontic site with a minimally invasive pouch technique. Participants either have an existing fixed partial denture that remains in place during treatment or no prosthesis, in which case a temporary bridge is provided during healing.
1 surgical visit and approximately 3 post-operative visits
Duration - 6 months
Participants undergo follow-up assessments over 6 months to evaluate healing, tissue stability, esthetic outcomes, and patient satisfaction.
Visits at 3 months and 6 months post-treatment, with additional visits for assessment of pain on days 3, 7, and 14
Trial Site Locations
Total: 1 location
1
Faculty of Dentistry, Cairo University
Cairo, Egypt, 12613
Actively Recruiting
Research Team
A
Ahmed Mohamed Elatreby, BDs
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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