Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
ID07535060

Clinical and Volumetric Evaluation of Soft Tissue Augmentation Using Connective Tissue Graft in Pontic Site Defects With and Without Fixed Partial Dentures

Led by Cairo University · Updated on 2026-05-01

20

Participants Needed

1

Research Sites

N/A

Total Duration

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AI-Summary

What this Trial Is About

Researchers are evaluating soft tissue augmentation using a connective tissue graft (CTG) in patients with pontic site defects, focusing on sites with and without an existing fixed partial denture (FDP). The study investigates whether performing CTG around an existing bridge can provide similar or improved clinical and volumetric outcomes compared to sites without a bridge. The goal is to address alveolar ridge resorption after tooth extraction, which often causes soft tissue problems affecting esthetics and function. Participants will undergo a standardized surgical procedure involving CTG harvested from the palate and placed at the pontic site using a minimally invasive pouch technique. The study compares two groups: those with pontic site defects and an existing FDP where the prosthesis remains during augmentation, and those without an FDP who will receive a temporary bridge during healing. All procedures occur under controlled clinical conditions with initial periodontal preparation. During the study, patients will have clinical and digital assessments before surgery and at follow-ups up to six months. Measurements include keratinized tissue thickness and width, volumetric soft tissue changes, esthetic scores, plaque index, post-operative pain, and patient satisfaction. Monitoring aims to evaluate healing, tissue stability, and esthetic results, supporting a less invasive treatment approach that may reduce discomfort and treatment time.

CONDITIONS

Brief Title

Pontic Site Development With or Without Fixed Partial Denture

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with a missing tooth in the esthetic zone (from 2nd premolar to 2nd premolar), missing for at least 3 months, with or without fixed partial denture
  • Systemically healthy patients
  • Age 18 years or older
  • Intact gum tissue with at least 2mm of keratinized tissue on adjacent teeth
  • Willingness to provide informed consent
Not Eligible

You will not qualify if you...

  • Smokers
  • Pregnant or breastfeeding women
  • Patients with periodontitis
  • Severe gagging reflex
  • Handicapped or mentally challenged patients
  • Active soft tissue infection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Single surgical procedure with post-operative care over 2 weeks

Participants receive soft tissue augmentation using a connective tissue graft (CTG) placed at the pontic site with a minimally invasive pouch technique. Participants either have an existing fixed partial denture that remains in place during treatment or no prosthesis, in which case a temporary bridge is provided during healing.

1 surgical visit and approximately 3 post-operative visits

Follow-up

Duration - 6 months

Participants undergo follow-up assessments over 6 months to evaluate healing, tissue stability, esthetic outcomes, and patient satisfaction.

Visits at 3 months and 6 months post-treatment, with additional visits for assessment of pain on days 3, 7, and 14

Trial Site Locations

Total: 1 location

1

Faculty of Dentistry, Cairo University

Cairo, Egypt, 12613

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Research Team

A

Ahmed Mohamed Elatreby, BDs

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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