Actively Recruiting
Population Pharmacokinetics of Anti-tuberculosis Drugs in Children With Tuberculosis
Led by Beijing Children's Hospital · Updated on 2018-08-15
800
Participants Needed
1
Research Sites
443 weeks
Total Duration
On this page
Sponsors
B
Beijing Children's Hospital
Lead Sponsor
S
Shandong University
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study is based on the hypothesis that the pharmacokinetics of anti-tuberculosis drugs in TB children are different from adults. The investigators aim to study the population pharmacokinetics of children receiving the anti-tuberculsis drugs for treatment of TB. In this study, the investigators will detect drug concentration in plasma by using residual blood samples of blood gas analysis and other clinical tests and employ computers for constructing population pharmacokinetic models. In addition, the investigators also want to correlate use of anti-tuberculsis drugs with treatment effectiveness and incidence of adverse effects in children. This novel knowledge will allow better and more rational approaches to the treatment of TB in children. It will also set the foundation for further studies to improve anti-tuberculosis drug therapies for children.
CONDITIONS
Official Title
Population Pharmacokinetics of Anti-tuberculosis Drugs in Children With Tuberculosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children aged 0 to 18 years with tuberculosis receiving anti-tuberculosis therapy
- Anti-tuberculosis therapy includes drugs commonly used for infectious diseases in children
- Informed consent signed by parents or guardians
You will not qualify if you...
- Children not treated with anti-tuberculosis drugs
- Unable to provide complete medical records or unable to participate in study procedures
- Known allergy to anti-tuberculosis drugs
- Parents or guardians do not consent to participation
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Beijing Children's Hospital of Capital Medical University
Beijing, China
Actively Recruiting
Research Team
A
A-Dong Shen, Master
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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