Perpetual Observational Study of Acute Respiratory Infections Presenting Via Emergency Rooms and Other Acute Hospital Care Settings

What this Trial Is About

Acute respiratory infections (ARI) are a common cause of hospital admissions and antibiotic use, caused by various pathogens including viruses like influenza and coronaviruses. This observational study aims to describe routine diagnostic and treatment practices for ARI and to characterize the adult patient population presenting with ARI in acute hospital settings across Europe. The study also seeks to understand the causes of ARI in these patients and variations in clinical outcomes. The study collects data from adults with ARI who visit emergency rooms or acute medical assessment units, including those admitted to hospital and those discharged the same day. Diagnostic methods such as laboratory and point of care tests, as well as pharmacological treatments like antibiotics and antivirals, are recorded. A subset of participants will have a respiratory sample taken within 24 hours to identify pathogens using molecular methods. Participants will undergo data collection about their clinical condition, laboratory tests, and treatments received. Researchers will track the use of microbiology and virology tests, antibiotic and antiviral treatments, clinical outcomes, hospital and ICU stays, and mortality up to 28 days after admission or discharge. Patient demographics, symptoms, comorbidities, physiological measurements, and ARI causes will also be studied. The study is ongoing and observational, with no direct interventions beyond data collection.

POS-ARI-ER Observational Study of Acute Respiratory Infections