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Does Position Influence the Diagnosis of Detrusor Overactivity in a Neurological Population - a Concordance Study Between Lying and Sitting Position
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-04-17
160
Participants Needed
1
Research Sites
N/A
Total Duration
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AI-Summary
What this Trial Is About
Researchers are investigating whether the position of the body during urodynamic exams affects the diagnosis of detrusor overactivity in people with neurological conditions such as Multiple Sclerosis (MS) or Parkinson's disease. Current recommendations suggest sitting or standing positions for these exams, but many neurological patients cannot maintain these positions during the test. The study aims to update guidance specifically for neurological patients by examining if the supine (lying down) position provides clear diagnostic information. Participants will undergo urodynamic exams in both lying and sitting positions during the same procedure. They will be randomly assigned to begin in either the lying or sitting position. The exam uses standardized filling speeds and equipment to measure bladder pressures and responses. Doctors will review the test data without knowing the patient's position to ensure unbiased results. Participants will have an initial consultation including questionnaires and clinical scales related to their condition. On the exam day, consent is obtained, and detailed data including bladder volume and pressure measurements are collected. Researchers will compare diagnosis results between the two positions over 24 months. The study also involves careful data recording and analysis to determine the best position for urodynamic testing in neurological patients.
CONDITIONS
Brief Title
Does Position Influence the Diagnosis of Detrusor Overactivity in a Neurological Population
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with Multiple Sclerosis or neurologically confirmed Parkinson's disease and scheduled for first urodynamic assessment
- Clinical overactive bladder syndrome with a USP overactive bladder sub-score of 4 or higher
- Age 18 years or older
- Men must have no prostatic hypertrophy confirmed by ultrasound
- Women must have no stress urinary incontinence or have a USP SUI subscore of 2 or less
- Affiliated with a social security scheme (excluding AME)
- Provided free and informed written consent
You will not qualify if you...
- Opposition to performing a urodynamic exam as part of treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - Up to 15 days before the urodynamic assessment
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for eligibility confirmation and information
Duration - 1 day
Participants undergo a urodynamic exam in both sitting and lying positions to diagnose detrusor overactivity.
1 visit (in-person) for urodynamic assessment including randomization of starting position
Duration - 24 months
Participants' diagnostic outcomes are observed and compared over 24 months to assess concordance between positions.
No scheduled visits; data collected from medical records and follow-up assessments
Trial Site Locations
Total: 1 location
1
Physical and Rehabilitation Medicine Pitié Salpêtrière Hospital
Paris, France, France, 75013
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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