Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID05949567

Does Position Influence the Diagnosis of Detrusor Overactivity in a Neurological Population - a Concordance Study Between Lying and Sitting Position

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-04-17

160

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating whether the position of the body during urodynamic exams affects the diagnosis of detrusor overactivity in people with neurological conditions such as Multiple Sclerosis (MS) or Parkinson's disease. Current recommendations suggest sitting or standing positions for these exams, but many neurological patients cannot maintain these positions during the test. The study aims to update guidance specifically for neurological patients by examining if the supine (lying down) position provides clear diagnostic information. Participants will undergo urodynamic exams in both lying and sitting positions during the same procedure. They will be randomly assigned to begin in either the lying or sitting position. The exam uses standardized filling speeds and equipment to measure bladder pressures and responses. Doctors will review the test data without knowing the patient's position to ensure unbiased results. Participants will have an initial consultation including questionnaires and clinical scales related to their condition. On the exam day, consent is obtained, and detailed data including bladder volume and pressure measurements are collected. Researchers will compare diagnosis results between the two positions over 24 months. The study also involves careful data recording and analysis to determine the best position for urodynamic testing in neurological patients.

CONDITIONS

Brief Title

Does Position Influence the Diagnosis of Detrusor Overactivity in a Neurological Population

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with Multiple Sclerosis or neurologically confirmed Parkinson's disease and scheduled for first urodynamic assessment
  • Clinical overactive bladder syndrome with a USP overactive bladder sub-score of 4 or higher
  • Age 18 years or older
  • Men must have no prostatic hypertrophy confirmed by ultrasound
  • Women must have no stress urinary incontinence or have a USP SUI subscore of 2 or less
  • Affiliated with a social security scheme (excluding AME)
  • Provided free and informed written consent
Not Eligible

You will not qualify if you...

  • Opposition to performing a urodynamic exam as part of treatment

AI-Screening

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Your Study Journey

Screening

Duration - Up to 15 days before the urodynamic assessment

Participants are screened for eligibility to participate in the trial.

1 visit (in-person) for eligibility confirmation and information

Diagnostic Evaluation

Duration - 1 day

Participants undergo a urodynamic exam in both sitting and lying positions to diagnose detrusor overactivity.

1 visit (in-person) for urodynamic assessment including randomization of starting position

Long-term Monitoring

Duration - 24 months

Participants' diagnostic outcomes are observed and compared over 24 months to assess concordance between positions.

No scheduled visits; data collected from medical records and follow-up assessments

Trial Site Locations

Total: 1 location

1

Physical and Rehabilitation Medicine Pitié Salpêtrière Hospital

Paris, France, France, 75013

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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