Actively Recruiting

Phase Not Applicable
Age: 18Years - 95Years
All Genders
NCT05412862

Positive Emotions Following Acute Cardiac Events

Led by Massachusetts General Hospital · Updated on 2026-04-20

280

Participants Needed

1

Research Sites

289 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The focus of this study is to test the efficacy of a 12-week, remotely delivered, positive-psychology-motivational interviewing (PP-MI) intervention, with additional twice weekly text messages for a total of 24 weeks (with interactive, algorithm-driven, goal-focused text messages in the final 12 weeks), compared to post-acute coronary syndrome (ACS) treatment as usual, in a randomized trial of 280 post-ACS patients with low baseline physical activity.

CONDITIONS

Official Title

Positive Emotions Following Acute Cardiac Events

Who Can Participate

Age: 18Years - 95Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of acute coronary syndrome (myocardial infarction or unstable angina)
  • Low physical activity level indicated by a score of less than 6 on the Medical Outcomes Study Specific Adherence Scale related to physical activity
Not Eligible

You will not qualify if you...

  • Cognitive deficits assessed by a 6-item cognitive screening tool
  • Medical conditions expected to cause death within 6 months
  • Moderate to severe depression with Patient Health Questionnaire-9 (PHQ-9) score of 15 or higher
  • Inability to participate in physical activity due to medical conditions such as arthritis
  • Inability to read, write, or speak English
  • Inability to receive text messages
  • Current participation in another program designed to promote well-being or physical activity

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114

Actively Recruiting

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Research Team

J

Jeff C Huffman, M.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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