Actively Recruiting

Phase 3
Age: 18Years +
MALE
NCT06056830

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

Led by Clarity Pharmaceuticals Ltd · Updated on 2026-05-14

383

Participants Needed

31

Research Sites

140 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim for this study is to assess the diagnostic performance of 64Cu-SAR-bisPSMA PET to detect regional nodal metastases.

CONDITIONS

Official Title

Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

Who Can Participate

Age: 18Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • At least 18 years of age
  • Signed informed consent
  • Untreated, histologically confirmed adenocarcinoma of the prostate
  • High-risk or greater prostate cancer defined by National Comprehensive Cancer Network Guidelines Version 1.202327 (clinical stage 223T3a, or Grade Group 2234, or PSA >20 ng/mL)
  • Patients electing to undergo radical prostatectomy with pelvic lymph node dissection
Not Eligible

You will not qualify if you...

  • Administration of any high energy (>300 KeV) gamma-emitting radioisotope within 5 physical half-lives prior to Day 1
  • Known or expected hypersensitivity to 64Cu-SAR-bisPSMA or any of its components
  • Patients with known predominant small cell or neuroendocrine prostate cancer

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 31 locations

1

University of Alabama Birmingham Hospital

Birmingham, Alabama, United States, 35249-6830

Actively Recruiting

2

Mayo Clinic- Phoenix

Phoenix, Arizona, United States, 85054

Actively Recruiting

3

Arkansas Urology Research Center, LLC

Little Rock, Arkansas, United States, 72211

Actively Recruiting

4

Urology Group of Southern California

Los Angeles, California, United States, 90017

Actively Recruiting

5

Greater Los Angeles VA Medical Center

Los Angeles, California, United States, 90073

Actively Recruiting

6

UC Irvine Health

Orange, California, United States, 92868

Actively Recruiting

7

Stanford University Medical Center

Stanford, California, United States, 94305-5105

Actively Recruiting

8

Mayo Clinic- Jacksonville

Jacksonville, Florida, United States, 32224

Actively Recruiting

9

Biogenix Molecular, LLC

Miami, Florida, United States, 33165

Actively Recruiting

10

NorthShore University Health System, Glenbrook Hospital

Glenview, Illinois, United States, 60026

Actively Recruiting

11

Indiana University School of Medicine

Indianapolis, Indiana, United States, 46202

Actively Recruiting

12

Wichita Urology Group

Wichita, Kansas, United States, 67226

Actively Recruiting

13

BAMF Health

Grand Rapids, Michigan, United States, 49503

Actively Recruiting

14

Corewell Health

Grand Rapids, Michigan, United States, 49503

Actively Recruiting

15

Mayo Clinic- Rochester

Rochester, Minnesota, United States, 55905

Actively Recruiting

16

XCancer Omaha LLC

Omaha, Nebraska, United States, 68130

Actively Recruiting

17

Mount Sinai Doctors Urology Faculty Practice

New York, New York, United States, 10029

Actively Recruiting

18

Duke University Medical Center

Durham, North Carolina, United States, 27710

Actively Recruiting

19

Urologic Specialists

Tulsa, Oklahoma, United States, 74146

Actively Recruiting

20

Oregon Urology

Springfield, Oregon, United States, 97477

Actively Recruiting

21

Carolina Urologic Research Center

Myrtle Beach, South Carolina, United States, 29572

Actively Recruiting

22

Urology Associates of Nashville

Nashville, Tennessee, United States, 37209

Actively Recruiting

23

Urology Clinics of North Texas

Dallas, Texas, United States, 75231

Actively Recruiting

24

University of Texas Southwestern Medical Center

Dallas, Texas, United States, 75390-8896

Actively Recruiting

25

The Urology Place

San Antonio, Texas, United States, 78240

Actively Recruiting

26

Intermountain Health

Murray, Utah, United States, 84107

Actively Recruiting

27

University of Wisconsin

Madison, Wisconsin, United States, 53705

Actively Recruiting

28

St. Vincent's Sydney

Sydney, New South Wales, Australia

Actively Recruiting

29

Princess Alexandra Hospital

Woolloongabba, Queensland, Australia

Actively Recruiting

30

Fiona Stanley Hospital

Murdoch, Western Australia, Australia, 6150

Actively Recruiting

31

Pan American Center for Oncology Trials, LLC - Ciudadela

San Juan, Puerto Rico, 00918

Actively Recruiting

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Research Team

C

Clarity Pharmaceuticals

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy | DecenTrialz