Actively Recruiting

Age: 30Years - 99Years
All Genders
NCT05539196

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

Led by InSightec · Updated on 2026-03-20

60

Participants Needed

5

Research Sites

340 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This registry is a prospective, multicenter, international, single arm, observational post-approval registry with follow-up at 3, 6, and 12 months, and annually for 5 years. The proposed registry will enroll 60 subjects and will be conducted at approximately 10 centers worldwide.

CONDITIONS

Official Title

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

Who Can Participate

Age: 30Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and women, age 30 years and older.
  • Subject undergoing a planned an Exablate procedure for their Parkinson's Disease with Motor Complications per local institution standard of care.
  • Subject is willing to cooperate with the Registry requirements including compliance with the regimen and completion of all Registry visits.
  • Subject has signed and received a copy of the approved informed consent form.
Not Eligible

You will not qualify if you...

  • Subject does not agree to participate or is unlikely to participate for the entirety of the Registry.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

University of Maryland, Baltimore

Baltimore, Maryland, United States, 21201

Actively Recruiting

2

Weill Cornell Medicine

New York, New York, United States, 10065

Actively Recruiting

3

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19106

Actively Recruiting

4

University of Texas Southwestern Medical Center

Dallas, Texas, United States, 75390

Actively Recruiting

5

Ohnishi Neurological Center

Akashi, Hyōgo, Japan, 674-0064

Actively Recruiting

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Research Team

K

Kingsley Nwaogu

CONTACT

J

Julia Zhu

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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