Actively Recruiting

Phase Not Applicable
Age: 21Years +
All Genders
Healthy Volunteers
NCT04770870

Post Approval Study2: Hintermann Series H3 Total Ankle Replacement System

Led by DT MedTech, LLC · Updated on 2024-06-25

232

Participants Needed

10

Research Sites

373 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The H3 TAR Prosthesis was approved by FDA (P160036) on June 4, 2019. Continued approval of the premarket approval application (PMA) is contingent upon the submission of periodic reports (Annual Report), required under 21 CFR 814.84. In order to provide continued reasonable assurance of the safety and effectiveness of the PMA device, data from this post-approval study must be submitted to FDA in a PMA Post-Approval Study Report per the requirements set forth in the approval.

CONDITIONS

Official Title

Post Approval Study2: Hintermann Series H3 Total Ankle Replacement System

Who Can Participate

Age: 21Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Be an appropriate candidate for mobile bearing total ankle replacement with a diagnosis of primary osteoarthritis, post-traumatic osteoarthritis, or arthritis secondary to inflammatory disease as determined by the Principal Investigator
  • Willingness to participate in the study and attend follow-up visits
  • Provide written informed consent, including permission to release collected health data
Not Eligible

You will not qualify if you...

  • Skeletal immaturity
  • Bone stock inadequate to support the device, including severe osteoporosis, osteopenia, or avascular necrosis of the talus
  • Active or prior deep infection in the ankle joint or adjacent bones
  • Severe malalignment or deformity of the foot or knee that prevents a plantigrade foot or proper function
  • Insufficient ligament support that cannot be repaired with soft tissue stabilization
  • Charcot joint or peripheral neuropathy affecting the ankle
  • Neuromuscular disease causing loss of normal muscle function around the ankle
  • Lower extremity vascular insufficiency shown by Doppler arterial pressure
  • Poor skin and soft tissue quality near the surgical site
  • Receiving immunosuppressive therapy
  • Prior ankle fusion or revision of total ankle replacement
  • Participation in high-demand sports such as contact sports or jumping
  • Known or suspected metal allergy or intolerance
  • Any condition that in the physician's opinion poses significant risk or interferes with study participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 10 locations

1

Los Angeles Institute of Foot and Ankle Surgery

Mission Hills, California, United States, 91345

Actively Recruiting

2

Florida Orthopedic Foot & Ankle Center

Sarasota, Florida, United States, 34233

Actively Recruiting

3

Paley Orthopedic & Spine Institute

West Palm Beach, Florida, United States, 33407

Actively Recruiting

4

Orthopaedic Associates

Evansville, Indiana, United States, 47710

Actively Recruiting

5

Department of Orthopedic Surgery, Johns Hopkins Outpatient Center

Baltimore, Maryland, United States, 21287

Actively Recruiting

6

New Mexico Bone and Joint Institute

Alamogordo, New Mexico, United States, 88310

Actively Recruiting

7

Duke Orhtopaedics Arringdon

Morrisville, North Carolina, United States, 27560

Actively Recruiting

8

Dept. of Orthopedic Surgery and Rehabilitation, University of Oklahoma

Oklahoma City, Oklahoma, United States, 73104

Terminated

9

MUSC Department of Orthopaedics/Foot and Anke Services

Charleston, South Carolina, United States, 29425

Actively Recruiting

10

Spring Branch Podiatry, PLLC

Houston, Texas, United States, 77024

Actively Recruiting

Loading map...

Research Team

I

In House Clinical Research Associate

CONTACT

S

Study Project Manager

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here