Actively Recruiting
Led by Walter Reed National Military Medical Center · Updated on 2026-01-27
148
Participants Needed
3
Research Sites
52 weeks
Total Duration
W
Walter Reed National Military Medical Center
Lead Sponsor
W
Womack Army Medical Center
Collaborating Sponsor
Musculoskeletal injuries (MSKI) and traumatic brain injury (TBI), especially concussions, are common and serious issues affecting military Service Members and physically active civilians. This research aims to identify how neuromuscular control changes after concussion may increase the risk of MSKI. The study will compare individuals who have had a concussion with those who have not, to understand the reasons behind this increased injury risk and help develop targeted prevention strategies. Participants will undergo detailed assessments including dynamic movement tests like jump-landing, single leg hop, anticipated cut, and gait tasks, along with strength and muscle activation tests. Sensory evaluations will assess proprioception and light touch sensation. These assessments occur at three time points: within 5 days of becoming asymptomatic post-concussion, then at 6 and 12 weeks after the initial assessment. Both concussed and matched non-concussed participants will complete the same testing and self-report psychosocial measures. During the study, participants will report any new musculoskeletal injuries and complete monthly questionnaires for about one year. Researchers will track changes in movement, muscle function, sensory abilities, and patient-reported outcomes over time. The study also monitors psychological factors such as anxiety, depression, and pain interference. This comprehensive approach will help measure how neuromuscular control evolves after concussion and its connection to injury risk.
CONDITIONS
Post-Concussion Musculoskeletal Injury Risks
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Initial visit plus follow-up assessments at 6 weeks and 12 weeks post-initial assessment (±72 hours)
Participants complete comprehensive neuromuscular, biomechanical, sensory, and psychosocial assessments to evaluate neuromuscular control and musculoskeletal injury risk following concussion.
3 visits (in-person) at initial, 6 weeks, and 12 weeks
Duration - Up to 1 year
Participants self-report musculoskeletal injuries and complete psychosocial questionnaires monthly to monitor changes over approximately one year following the initial assessment.
Monthly remote assessments via email or internet
Total: 3 locations
1
University of Georgia
Athens, Georgia, United States, 30602
Actively Recruiting
2
Walter Reed National Military Medical Center
Bethesda, Maryland, United States, 20814
Actively Recruiting
3
Womack Army Medical Center
Fort Bragg, North Carolina, United States, 28310
Active, Not Recruiting
B
Bradford D Hendershot, PhD
J
Joseph G Wasser, PhD
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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Robert C Lynall, Joseph G Wasser, Daniel I Brooks...
https://pubmed.ncbi.nlm.nih.gov/36948547