Actively Recruiting
Post COVID-19 Syndrome Treatment With Variable Pulse Transcranial Magnetic Stimulation
Led by Mayo Clinic · Updated on 2025-08-14
40
Participants Needed
1
Research Sites
88 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to test if Variable Pulse TMS (Transcranial Magnetic Stimulation) can result in objective improvements in patients with Post COVID Syndrome (PCS).
CONDITIONS
Official Title
Post COVID-19 Syndrome Treatment With Variable Pulse Transcranial Magnetic Stimulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with a recent COVID-19 episode presenting to Mayo Clinic's Post COVID-19 Clinic
- At least one symptom of Post COVID Condition (anosmia, tinnitus, or fatigue) lasting more than 4 weeks after a positive COVID-19 test
- Anosmia confirmed by Olfactory Threshold Test scores indicating anosmia or hyposmia
- Tinnitus with a score above 0 on the Tinnitus Handicap Inventory, not present before COVID-19 infection
- Fatigue with a Modified Fatigue Impact Scale score of 40 or above
You will not qualify if you...
- Implanted electronic devices like pacemakers, defibrillators, medication pumps, or vagus nerve stimulators
- Active alcohol abuse exceeding 14 drinks per week, illicit drug use, or drug abuse
- Seizure history within the past 10 years
- Intracranial metal implants or objects near the head that cannot be safely removed
- Enrollment in another interventional trial during this study
- Previous stroke with lasting deficits
- Inability to understand or follow verbal commands
- Inability to provide informed consent
- Medical conditions or instability judged by investigators to pose safety risks or interfere with study results
- Pregnant or trying to become pregnant; negative pregnancy test required for women of childbearing potential
- Any condition preventing completion of the study as judged by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
D
Department of Medicine Research Hub, Coordinator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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