Actively Recruiting
Post-Discharge Risk-Based Management in Patients Undergoing High-Risk Elective Major Cancer Operations (PRS II)
Led by Fox Chase Cancer Center · Updated on 2025-07-08
880
Participants Needed
1
Research Sites
315 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a randomized trial of intensified post-discharge surveillance (Intervention Arm) versus standard post-discharge surveillance (Control Arm).
CONDITIONS
Official Title
Post-Discharge Risk-Based Management in Patients Undergoing High-Risk Elective Major Cancer Operations (PRS II)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years at diagnosis
- ECOG performance status of 0, 1, or 2 (fully active or ambulatory with some activity restrictions but able to care for self)
- Probable or confirmed primary or recurrent malignant neoplasm, neuroendocrine tumor, or carcinoma in situ at any stage
- Scheduled for elective major cancer surgery at FCCC within 30 days after registration
- Surgery must be elective (not urgent or emergency) with planned admission from home
- Ability to understand and sign informed consent and HIPAA documents
- Willingness and ability to return to FCCC for all preoperative and postoperative study assessments
- Undergoing major operations to treat malignancies of head and neck, chest, abdomen, genitourinary tract, or extremities
You will not qualify if you...
- Undergoing biopsies, outpatient procedures, superficial resections of skin cancers, or purely palliative operations
- Any condition interfering with study participation, compliance, or evaluation
- Undergoing elective surgery not listed in the Surgical Risk Calculator at second registration
- Patients whose scheduled procedure was suspended due to unexpected findings such as carcinomatosis
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Fox Chase Cancer Center - Philadelphia
Philadelphia, Pennsylvania, United States, 19111-2497
Actively Recruiting
Research Team
J
Jason Castellanos, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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