Study on Preventing Pancreatitis After ERCP Procedures in Adults

What this Trial Is About

Researchers are conducting a prospective, observational study across multiple centers in Slovakia and Czechia to understand how often inflammation of the pancreas, called post-ERCP pancreatitis PEP, occurs after an endoscopic procedure known as ERCP. The study aims to monitor PEP rates as a measure of patient safety and quality of care during ERCP, which is used to treat bile duct and pancreas problems. It will also evaluate how well hospitals follow prevention guidelines from major professional societies and how these measures impact the risk of PEP. The study includes adult patients undergoing their first ERCP or a repeat ERCP after a previous failed cannulation. Patients with certain prior procedures, anatomical issues, or complications preventing standard ERCP are excluded. The ERCP procedure is performed under analgosedation or general anesthesia based on patient condition and hospital protocols. This observational study does not involve experimental treatments but carefully records the procedures and preventive measures used. Participants will be observed closely for the development of PEP up to 48 hours post-procedure, with severity assessments every 7 days until hospital discharge. The study tracks the use of recommended preventive measures before, during, or shortly after ERCP, monitors risk factors, and records any PEP-related death within 30 days. This data will help improve understanding of PEP occurrence and prevention in real-world clinical settings.

Post-ERCP Pancreatitis - Prophylactic Measures Implementation Study (PEP-PROMIS)