Comparing Bone Healing After Tooth Extraction Using Autogenous Partially Demineralized Dentin Graft Versus Xenograft in the Esthetic Zone

What this Trial Is About

Researchers are evaluating the differences between using a partially demineralized autogenous dentin graft and a xenograft in bone regeneration after tooth extraction in the esthetic zone. The study focuses on clinical, radiographic, and histomorphometric outcomes related to alveolar ridge preservation in patients requiring extraction of non-restorable teeth. This research aims to compare the effects of these two graft materials on hard tissue changes following extraction and ridge preservation procedures. Participants will undergo initial periodontal therapy including cleaning and polishing, followed by atraumatic tooth extraction. The sockets will be filled with either the autogenous dentin graft prepared by a specialized device or a bovine xenograft, both covered with a collagen membrane secured by sutures. The study includes a test group receiving the dentin graft and a control group receiving the xenograft. After six months, bone biopsies and implant placements will be performed to evaluate the healing and regenerative outcomes. Participants will be assessed before surgery, immediately after, and six months post-surgery using clinical parameters and cone-beam CT scans to measure horizontal ridge width and ridge height changes. Histological analysis will determine new bone formation and residual graft presence. Implant primary stability will also be evaluated. Postoperative care includes antibiotics, pain management, oral hygiene instructions, and suture removal after two weeks. The total follow-up period for each participant is six months.

Post Extraction Alterations Following Ridge Preservation In The Esthetic Zone Using Partially Demineralized Autogenous Dentine Graft Versus Xenograft