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Comparison of Allogenic Dentin Matrix and Autogenous Partially Demineralized Dentin Matrix for Ridge Preservation After Tooth Extraction in the Aesthetic Zone
Led by Cairo University · Updated on 2024-08-06
32
Participants Needed
1
Research Sites
17 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying how well two types of dentin matrix grafts help preserve the bone after tooth extraction in the smile area, called the aesthetic zone. The study compares an allogenic dentin matrix, which is processed from donor teeth, with an autogenous partially demineralized dentin matrix APDDM, made from the patients own extracted tooth. The goal is to see which method better reduces hard tissue changes and supports bone healing. This clinical trial is randomized and controlled to provide reliable comparisons. The allogenic dentin matrix undergoes a detailed cleaning and processing procedure including washing, ultrasonic cleaning, defatting, demineralization, dehydration, freeze-drying, and sterilization before being placed in the extraction socket. The autogenous dentin is cleaned, ground using a special device, partially demineralized, and then packed into the socket. Both groups have the graft covered with a collagen membrane that is secured with sutures. After six months of healing, a biopsy sample will be collected during implant placement to evaluate the bone formation. Participants will visit the clinic for periodontal and radiographic exams before treatment. After tooth extraction and graft placement, they will be monitored over a six-month period, including radiographic imaging to measure bone changes and bone width loss. Researchers will also assess vital new bone formation, the presence of residual graft material, and the stability of dental implants placed later. This study involves outpatient visits and tissue sampling to fully understand the healing outcomes.
CONDITIONS
Brief Title
Post Extraction Changes Following Ridge Preservation Using Allogenis Dentin Vs Autogenous Partially Demineralized Dentin
Research Team
A
Abdullah Matar
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