Actively Recruiting

Age: 1Year - 18Years
All Genders
NCT07448740

Post-failure Stepwise Heat-Denaturated Protein Introduction for Tolerance Induction in Cow's Milk Allergy Observational Cohort Study

Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2026-03-04

30

Participants Needed

5

Research Sites

290 weeks

Total Duration

On this page

Sponsors

U

Universitaire Ziekenhuizen KU Leuven

Lead Sponsor

J

Jessa Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

Subjects who failed to become tolerant within 12 months after randomization within one of the three arms in the TEHITI study, can participate in the post-TEHITI observational trial to study the natural tolerance induction process.

CONDITIONS

Official Title

Post-failure Stepwise Heat-Denaturated Protein Introduction for Tolerance Induction in Cow's Milk Allergy Observational Cohort Study

Who Can Participate

Age: 1Year - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participation in the s68299 study
  • Failed challenge test with unheated cow's milk
  • Passed challenge test with heated cow's milk but developed symptoms related to cow's milk intake at home between challenge and termination visit
Not Eligible

You will not qualify if you...

  • Not previously enrolled in the s68299 study
  • Passed challenge test and have no complaints with regular cow's milk consumption at termination visit
  • Refuse to consent or assent to the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

Imelda Hospital

Bonheiden, Belgium

Actively Recruiting

2

AZ Sint Jan

Bruges, Belgium

Actively Recruiting

3

AZ Maria Middelares

Ghent, Belgium

Actively Recruiting

4

Jessa Hospital

Hasselt, Belgium

Actively Recruiting

5

UZ Leuven Gasthuisberg

Leuven, Belgium

Actively Recruiting

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Research Team

D

Dominique MA Bullens, Prof, MD

CONTACT

M

Marleen Jannis

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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