Actively Recruiting

Age: 18Years - 100Years
All Genders
NCT06008080

Post-Market Clinical Follow Up Study With Navitor Valve

Led by Abbott Medical Devices · Updated on 2025-06-06

1000

Participants Needed

35

Research Sites

426 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Evaluation of the safety and performance of the Navitor TAVI System in a Global Study

CONDITIONS

Official Title

Post-Market Clinical Follow Up Study With Navitor Valve

Who Can Participate

Age: 18Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient is eligible per the current approved indication after Heart Team discussion and intended to undergo a Navitor TAVI procedure.
  • The patient has been informed of the nature of the study, agrees to its provisions, and has provided written informed consent as approved by the IRB/EC of the respective clinical site.
  • The patient and the treating physician agree that the subject will return for all required post procedure follow up visits.
Not Eligible

You will not qualify if you...

  • Patient is not eligible for the Navitor TAVI System per the current Instructions for Use (IFU).
  • Life expectancy less than 12 months from the time of informed consent due to non-cardiac co-morbid conditions.
  • In the judgment of the Investigator, patient presents with a medical, social, or psychological condition that could limit the ability or willingness to participate in the study, comply with study required testing and/or follow-up visits or that could impact scientific integrity of the study.
  • Known contraindication for computed tomography (CT) or sensitivity to contrast media, which cannot be adequately premedicated.
  • Inability to tolerate antiplatelet/anticoagulation therapy or nitinol alloy (nickel and titanium), which cannot be adequately premedicated.
  • Currently participating in an investigational drug or device study that may confound the results of this study.
  • Anatomy that makes insertion and endovascular access to the aortic valve difficult and/or impossible.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 35 locations

1

Royal Hobart Hospital

Hobart, Australia

Actively Recruiting

2

Clinique du Millénaire

Montpellier, France

Actively Recruiting

3

Mutualiste Montsouris

Paris, France

Actively Recruiting

4

CHRU Hopital de Pontchaillou

Rennes, France

Actively Recruiting

5

Clinique Pasteur Toulouse

Toulouse, France

Actively Recruiting

6

Herz- u. Gefäßzentrum Bad Bevensen

Bad Bevensen, Germany

Actively Recruiting

7

Deutsches Herzzentrum der Charité

Berlin, Germany

Actively Recruiting

8

St Johannes Hospital Dortmund

Dortmund, Germany

Actively Recruiting

9

Kliniken der Friedrich-Alexander-Universitat

Erlangen, Germany

Actively Recruiting

10

Klinikum der Johann Wolfgang Goethe-Universität Frankfurt

Frankfurt, Germany

Actively Recruiting

11

UKE Hamburg

Hamburg, Germany

Actively Recruiting

12

Universitätsklinikum Schleswig-Holstein - Campus Kiel

Kiel, Germany

Actively Recruiting

13

Deutsches Herzzentrum München des Freistaates Bayern

München, Germany

Actively Recruiting

14

University Hospital Rostock

Rostock, Germany

Actively Recruiting

15

Universitätsklinikum Ulm

Ulm, Germany

Actively Recruiting

16

Az. Osp. Spedali Civili di Brescia

Brescia, Italy

Actively Recruiting

17

Casa di Cura Pineta Grande

Castel Volturno, Italy

Actively Recruiting

18

Centro Cardiologico Monzino

Milan, Italy

Actively Recruiting

19

Ospedale San Raffaele - Cardiac

Milan, Italy

Actively Recruiting

20

Policlinico San Donato

San Donato Milanese, Italy

Actively Recruiting

21

Onze Lieve Vrouw Gasthuis

Amsterdam, Netherlands

Actively Recruiting

22

ULS de Lisboa Ocidental

Carnaxide, Portugal

Actively Recruiting

23

Hospital Universitario de Badajoz

Badajoz, Spain

Active, Not Recruiting

24

Hospital Clinic de Barcelona

Barcelona, Spain

Actively Recruiting

25

Hospital de la Santa Creu I Sant Pau

Barcelona, Spain

Actively Recruiting

26

Hospital General Juan Ramon Jimenez

Huelva, Spain

Actively Recruiting

27

Hospital de Gran Canaria Doctor Negrín

Las Palmas, Spain

Actively Recruiting

28

Hospital Universitario Puerta de Hierro

Majadahonda, Spain

Actively Recruiting

29

Consorcio Hospital General Universitario de Valencia

Valencia, Spain

Actively Recruiting

30

Sahlgrenska University Hospital - Gothenburg

Gothenburg, Sweden

Actively Recruiting

31

KS St. Gallen / USZ

Sankt Gallen, Switzerland

Actively Recruiting

32

Kings College Hospital

London, United Kingdom

Actively Recruiting

33

James Cook University Hospital

Middlesbrough, United Kingdom

Active, Not Recruiting

34

Royal Stoke University Hospital

Stoke-on-Trent, United Kingdom

Actively Recruiting

35

New Cross Hospital

Wolverhampton, United Kingdom

Actively Recruiting

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Research Team

B

Bart Janssens

CONTACT

A

Alicia Kimber

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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