Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT06574022

Post-mastectomy Recovery: Comparing Preoperative PECS-II Blocks With Intraoperative Pectoral Blocks

Led by University of Cincinnati · Updated on 2025-11-04

100

Participants Needed

1

Research Sites

113 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose this research is to compare two different standards of care for pain management and two different standards of care for local numbing medicine for breast cancer patients who will have a total mastectomy.

CONDITIONS

Official Title

Post-mastectomy Recovery: Comparing Preoperative PECS-II Blocks With Intraoperative Pectoral Blocks

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients who are 18 years of age or older
  • Patients undergoing mastectomy with or without axillary surgery, with or without reconstruction surgery at UCMC for breast cancer or high-risk of breast cancer
  • Patients considered high-risk include those with atypical/precancerous breast lesions, genetic mutations increasing cancer risk (e.g., BRCA1, BRCA2), or strong family history of breast cancer as determined by the investigator
Not Eligible

You will not qualify if you...

  • Patients undergoing only a partial mastectomy or tissue-based reconstruction
  • Non-English speaking patients
  • Pregnant patients
  • Patients allergic to local anesthetics (except those allergic only to topical anesthetics)
  • Patients with acute or chronic pain disorder prescribed opioids within 30 days before surgery (exceptions considered case-by-case)
  • Patients with a history of opioid use disorder
  • Patients unable to provide informed consent
  • Patients deemed by the investigator as unreliable for follow-up or unsuitable for participation

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Cincinnati Medical Center

Cincinnati, Ohio, United States, 45219

Actively Recruiting

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Research Team

U

UCCC Clinical Trials Office

CONTACT

A

Alicia Heelan, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

4

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Post-mastectomy Recovery: Comparing Preoperative PECS-II Blocks With Intraoperative Pectoral Blocks | DecenTrialz