Actively Recruiting

Phase 1
Phase 2
Age: 50Years +
MALE
Healthy Volunteers
NCT03609580

Post-operative Urinary Retention (POUR) Following Thoracic Surgery

Led by Hackensack Meridian Health · Updated on 2025-10-24

127

Participants Needed

1

Research Sites

412 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Inability to urinate a common complication that happens to many patients after a surgery, especially in men over 60 years of age who undergo surgery on their chest. Urinary retention is uncomfortable, increases anxiety, increases hospital length of stay, and leads to more procedures such as putting in a bladder catheter (Foley). This is uncomfortable, and can lead to bleeding, infection, damage to the urethra and/or bladder and bladder spasm. The goal of this study is to attempt to prevent inability to urinate by giving patients a medication called Flomax (Tamusolin) every day beginning a week before surgery. That medication relaxes the prostate. It's approved by the Food and Drug Administration (FDA) to improve urinary flow in those with enlarged prostates. It is also commonly used in patients with bladder problems due to inability to urinate who have required a Foley.

CONDITIONS

Official Title

Post-operative Urinary Retention (POUR) Following Thoracic Surgery

Who Can Participate

Age: 50Years +
MALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male
  • Age 50 years or older
  • Planned minimally invasive thoracic surgery (wedge resection, segmentectomy, lobectomy, pleural biopsy, or pleurodesis)
  • Surgery scheduled at least 3 days after consent
Not Eligible

You will not qualify if you...

  • Currently using Flomax
  • Allergy to Flomax or sulfa drugs
  • Current use of alpha blockers or alpha agonists
  • Resting systolic blood pressure less than 100 mm Hg
  • Orthostatic hypotension over 20 mm Hg systolic or 10 mm Hg diastolic after standing for 2 minutes
  • Known congestive heart failure or valvular heart disease
  • History of prostate surgery such as prostatectomy or trans-urethral resection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Daniel Mansour

Hackensack, New Jersey, United States, 07601

Actively Recruiting

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Research Team

D

Daniel Mansour, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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