Actively Recruiting
Post Operative Urinary Retention (POUR) Following Thoracic Oncological Surgery
Led by Hackensack Meridian Health · Updated on 2026-02-10
46
Participants Needed
4
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate whether the use of Tamsulosin can reduce the high rate of postoperative urinary retention (POUR) in older men undergoing thoracic cancer surgery. POUR is a common issue, especially in older men with enlarged prostates, leading to urinary tract infections, discomfort, and longer hospital stays. This pilot study focuses on men aged 55 and older scheduled for oncological thoracic surgery to see if Tamsulosin can help lower POUR incidence and identify when normal urinary function returns after surgery. Participants will receive a prescription for Tamsulosin at a dose of 0.4 mg daily, starting seven days before their planned surgery and continuing up to the day of surgery. They will take the medication with a meal and record their daily usage in a diary. After surgery, bladder function will be monitored using ultrasound to measure urine volume and residual urine. If spontaneous urination does not occur or excess urine remains, standard bladder management including intermittent catheterization may be applied based on specific guidelines. During the study, researchers will observe and record whether participants can urinate spontaneously within 6 to 8 hours after surgery, the timing and volume of urination within 24 hours, and the amount of residual urine. Those unable to urinate spontaneously may receive catheter interventions. The study will include regular assessments using a BladderScanner and follow participants until urinary function resumes. The total study duration varies depending on surgery and recovery timelines.
CONDITIONS
Brief Title
Post Operative Urinary Retention (POUR) Following Thoracic Oncological Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male sex
- 55 years of age or older
- Scheduled for a thoracic oncological surgical procedure for suspected or confirmed cancer
- Surgery scheduled at least 7 days after giving consent
You will not qualify if you...
- Currently using Tamsulosin
- Known allergy to Tamsulosin or sulfa drugs
- Current use of Boceprevir
- Resting systolic blood pressure less than 100 mm Hg
- Orthostatic hypotension with more than 20 mm Hg systolic or 10 mm Hg diastolic drop after standing for 2 minutes
- History of hypotension
- Known congestive heart failure or valvular heart disease
- History of prior prostate surgery such as prostatectomy or trans-urethral resection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 7 days
Participants take Tamsulosin daily for seven days prior to their scheduled thoracic oncological surgery.
Daily medication intake with a diary to record usage
Duration - Up to 24 hours post surgery
Participants undergo thoracic oncological surgery followed by bladder ultrasound approximately six hours after surgery to assess urinary retention. Bladder management interventions are provided if needed based on ultrasound results and ability to void.
1 post-surgical assessment visit (in-person)
Trial Site Locations
Total: 4 locations
1
Ocean University Medical Center
Brick, New Jersey, United States, 08724
Actively Recruiting
2
South Ocean University Medical Center
Manahawkin, New Jersey, United States, 08050
Actively Recruiting
3
Jersey Shore University Medical Center
Neptune City, New Jersey, United States, 07753
Actively Recruiting
4
Riverview Medical Center
Red Bank, New Jersey, United States, 07701
Actively Recruiting
Research Team
D
Denise Theiler, RN
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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