Prediction of Gastroesophageal Reflux Disease After Sleeve Gastrectomy Using EndoFLIP Device

What this Trial Is About

Researchers are investigating how to predict gastroesophageal reflux disease GERD that may develop after sleeve gastrectomy, a type of weight-loss surgery. This study focuses on assessing parameters from an endoscopy and a device called EndoFLIP to help identify risk factors for GERD following the surgery. The research is sponsored by Mayo Clinic and involves adult patients undergoing bariatric surgery. Participants will have an upper endoscopy combined with EndoFLIP measurements before their sleeve gastrectomy to collect key data about the gastroesophageal junction and esophageal function. If clinically needed, a repeat endoscopy with EndoFLIP may be performed six months after surgery. Follow-up includes completing questionnaires for up to five years to monitor any changes. During the study, participants will undergo these procedures and assessments at baseline, with possible repeat testing at six months, and ongoing follow-up visits up to five years. The main outcome measured is the development or worsening of GERD symptoms after surgery. Researchers will use the collected data to develop models predicting GERD risk. This long-term monitoring aims to improve understanding and management of complications after sleeve gastrectomy.

Post-sleeve Gastrectomy Gastroesophageal Reflux Disease Prediction