Actively Recruiting

Age: 30Weeks - 83Months
All Genders
NCT05336890

Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age

Led by Ann & Robert H Lurie Children's Hospital of Chicago · Updated on 2024-12-05

500

Participants Needed

1

Research Sites

191 weeks

Total Duration

On this page

Sponsors

A

Ann & Robert H Lurie Children's Hospital of Chicago

Lead Sponsor

U

University of Virginia

Collaborating Sponsor

AI-Summary

What this Trial Is About

Despite improved survival of extremely premature infants in recent decades, neonatal intensive care unit (NICU) graduates are diagnosed with asthma, sleep disordered breathing (SDB) in childhood, and neurodevelopmental impairments (NDI) at significant rates, disproportionate to their term peers. Early detection and intervention are critical to mitigate the impact of these impairments. Mechanisms leading from premature birth to these undesirable outcomes remain unclear, and accurate prognostic measures are lacking. This study wants to learn if these problems are related to certain patterns of breathing that babies had while they were in the NICU.

CONDITIONS

Official Title

Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age

Who Can Participate

Age: 30Weeks - 83Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Enrolled in any IRB-approved Pre-Vent Study protocol with signed consent or authorized re-contact
  • Born before 29 weeks gestational age
  • Younger than 7 years old at enrollment
Not Eligible

You will not qualify if you...

  • Withdrawn from the Pre-Vent study after signing consent
  • No physiological data recorded as part of Pre-Vent
  • No regulatory approval from local IRB or Department of Children and Family Services to recontact
  • Adopted by a non-consenting family
  • Parent refused further contact before Post-Vent approach
  • Infant enrolled in Pre-Vent at Washington University St Louis (not a Post-Vent site)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, United States, 60611

Actively Recruiting

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Research Team

E

Erin Smith Lonergan

CONTACT

C

Casey Rand

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age | DecenTrialz