Actively Recruiting

Phase 4
Age: 18Years - 100Years
All Genders
NCT06353529

Postop Pain Management in Pituitary Tumour Patients

Led by Hamilton Health Sciences Corporation · Updated on 2026-03-12

108

Participants Needed

1

Research Sites

83 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To assess the benefit of using an additional nerve block during minimally invasive pituitary surgery, to improve pain management after surgery. The medication (Bupivacaine) or a placebo (saline) will be injected during surgery and patients will be asked about their level of pain at multiple time points in the first 24 hours following surgery. Some patients will be randomized to a third, sham group that do not receive any additional injection. The aim is to improve patient outcomes and reduce the need for pain medication after surgery.

CONDITIONS

Official Title

Postop Pain Management in Pituitary Tumour Patients

Who Can Participate

Age: 18Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients 18 years or older
  • Undergoing endonasal pituitary adenoma resection
Not Eligible

You will not qualify if you...

  • Chronic pain conditions requiring antidepressants, benzodiazepines, gabapentin, or opioid drugs
  • Known allergy to medications used in the nerve block
  • Chronic alcohol abuse
  • Uncontrolled systemic arterial hypertension
  • Severe kidney or liver diseases
  • Cardiomyopathies or sustained cardiac arrhythmias such as permanent or paroxysmal atrial fibrillation or other sustained supraventricular rhythm problems

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hamilton General Hospital

Hamilton, Ontario, Canada, L8L 2X2

Actively Recruiting

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Research Team

D

Dr. Kesava Reddy, MD

CONTACT

M

Ms. Jessy Moore, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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