Actively Recruiting
Postoperative Adjuvant Chemotherapy for Thymic Cancer (FUSCC-Thymic 3)
Led by Fudan University · Updated on 2026-04-27
172
Participants Needed
1
Research Sites
316 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn the role of adjuvant chemotherapy for patients with thymic carcinoma and completed resection. The main questions it aims to answer are: 1. Does adjuvant chemotherapy decrease disease progression? 2. Does medium dose of three drugs (paclitaxel, cisplatin, 5-FU) well tolerance? Researchers will compare chemoradiotherapy to radiotherapy to see whether chemoradiotherapy could decrease disease progression or not. Participants will: 1. Take radiotherapy (50Gy/25f) with or without 4 cycles of chemotherapy (TPF). 2. Follow up every 3 months in the first two year, and then every 6 months.
CONDITIONS
Official Title
Postoperative Adjuvant Chemotherapy for Thymic Cancer (FUSCC-Thymic 3)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Volunteer and sign informed consent
- Aged 18 to 75 years old
- Surgery completed within the past 3 months
- Histologically confirmed thymic cancer
- Complete tumor removal confirmed by surgery and imaging
- Masaoka stage I to III disease
- No severe dysfunction of blood, heart, lung, liver, kidney, or immune system
- Blood counts and liver/kidney tests within specified normal limits
You will not qualify if you...
- Having a second primary tumor, except certain cured or low-risk cancers
- Symptomatic coronary heart disease, left heart failure, uncontrolled seizures, or loss of consciousness due to mental illness
- Pregnant or breastfeeding
- Drug addiction, chronic alcoholism, or AIDS
- Deemed unsuitable by researchers
AI-Screening
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Trial Site Locations
Total: 1 location
1
Fudan University Shanghai Cancer Center
Shanghai, Shanghai Municipality, China, 212013
Actively Recruiting
Research Team
X
Xingwen Fa, Doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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