Actively Recruiting
Postoperative Analgesia Between Paravertebral Block and Epidural Block in Esophageal Surgery
Led by Zhejiang Cancer Hospital · Updated on 2024-12-30
132
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Prevention of postoperative pain is essential for the recovery of esophageal surgery. Epidural analgesia is a traditional and standard perioperative pain management for these patients. Beneficials of epidural analgesia have been widely established. However, there are still several potential disadvantages such as perioperative hypotension, failure of administration, rare but serious neurological complications. Ultrasound-guided regional nerve block has become a widely used technique due to its low degree of trauma and precise target of action. In combined with liposome bupivacaine (LB), a new long-acting local anesthetic, was proven to have a maximum duration of 72 hours, thus improving postoperative analgesia, reducing opioid consumption, and enhancing patient satisfaction. The aim of this study was to evaluate the efficacy of TPVB liposomal bupivacaine (LB) or plane bupivacaine (SB) for Overall Benefit of Analgesic Score (OBAS) after esophageal surgery.
CONDITIONS
Official Title
Postoperative Analgesia Between Paravertebral Block and Epidural Block in Esophageal Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- American Society of Anesthesiologist physical status I-III
- Scheduled elective thoracoscopic esophagectomy (three-incision approach)
- Approved participation before study
You will not qualify if you...
- Contraindications for local nerve block such as spinal anatomic abnormalities or infection at puncture site
- Allergy to medications used in this study
- Chronic pain
- Current use of anticoagulants or opioids, or history of narcotic or alcohol abuse
- Inability to complete postoperative pain assessments or questionnaires due to communication barriers or mental disorders
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Jiangling Wang
Hangzhou, Zhejiang, China, 310022
Actively Recruiting
Research Team
J
Jiangling Wang, M.D
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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