Actively Recruiting
Postoperative Hypofractionated Radiation in Cervical and Endometrial Tumours: Phase II Study
Led by Tata Memorial Centre · Updated on 2025-04-15
90
Participants Needed
2
Research Sites
312 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary aim of the trial is to investigate the late effects of hypofractionated external radiation (39 Gy in 13 fractions) in patients requiring post-operative radiation for early-stage cervical and endometrial cancers.
CONDITIONS
Official Title
Postoperative Hypofractionated Radiation in Cervical and Endometrial Tumours: Phase II Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2
- Histologically confirmed cervical cancer after hysterectomy with intermediate or high-risk features needing adjuvant external beam radiation therapy with or without concurrent chemotherapy
- Histologically confirmed endometrial cancer after hysterectomy requiring adjuvant chemotherapy and/or radiation to the pelvis with or without vaginal brachytherapy
You will not qualify if you...
- Presence of visible residual tumor after surgery (R+ resection)
- Need for extended field radiotherapy due to involved para-aortic lymph nodes
- Previous chemotherapy treatment for any cancer
- Prior pelvic radiation therapy
- Human immunodeficiency virus (HIV) infection
- Existing medical conditions that could affect evaluation of genitourinary or gastrointestinal toxicity, such as irritable bowel syndrome, intestinal obstruction, anal incontinence, hemorrhoids, urinary incontinence, or recurrent urinary tract infections
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Advanced Centre for Treatment Research and Education in Cancer (ACTREC)
Navi Mumbai, Maharahstra, India, 410210
Actively Recruiting
2
Tata Memorial Hospital
Mumbai, Maharashtra, India, 400012
Actively Recruiting
Research Team
D
Dr. Prachi D Mittal, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here