Actively Recruiting
Assessment of Postoperative Pain in Patients Obturated With Bioceramic and Calcium Hydroxide Sealers: A Randomized Clinical Trial
Led by HITEC-Institute of Medical Sciences · Updated on 2026-02-17
50
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
The trial investigates how two types of root canal sealers, bioceramic and calcium hydroxide-based, affect pain after root canal treatment in patients diagnosed with symptomatic irreversible pulpitis. This randomized controlled clinical trial aims to better understand postoperative discomfort, a common issue that can impact patient satisfaction and perceived treatment success. The study will enroll 50 participants aged 18 to 40 years, with single-rooted permanent teeth needing treatment, conducted at a dental college over six months to one year. Participants will receive standard root canal treatment in a single visit by the same dentist to reduce variability. The canals will be prepared and irrigated, then filled using a single-cone technique with either a bioceramic sealer (CeraSeal) or a calcium hydroxide sealer (Sealapex), both sealed with glass ionomer cement. Postoperative pain will be recorded by patients using a Visual Analog Scale (VAS) at 12, 24, 48, and 72 hours after treatment. No postoperative medications will be prescribed. During the study, participants will report pain levels at scheduled times, and any analgesic use will be noted. The collected data will be analyzed to compare pain between the two sealer groups. Confidentiality is ensured by anonymizing all data. The main outcome measured is postoperative pain at these time points to help dentists better choose sealers that may reduce discomfort after root canal therapy.
CONDITIONS
Brief Title
Postoperative Pain After Root Canal Obturation Using Bioceramic and Calcium Hydroxide Sealers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 to 40 years
- Single-rooted permanent teeth
- Teeth diagnosed with symptomatic irreversible pulpitis
- Normal periapical condition on radiographic examination or periodontal ligament (PDL) space widening
- Restorable teeth
You will not qualify if you...
- Patients with systemic conditions that could alter the course of treatment
- Teeth with immature root development
- Teeth with necrotic pulp
- Teeth exhibiting root resorption
- Teeth with calcified root canals
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for diagnosis and eligibility confirmation
Duration - 1 day
Participants undergo a single root canal treatment visit where the canal is prepared, irrigated, and obturated using either a bioceramic or calcium hydroxide sealer. The access cavity is restored with glass ionomer cement and occlusal reduction is performed to minimize postoperative discomfort.
1 treatment visit (in-person)
Duration - 72 hours
Participants record postoperative pain using a Visual Analog Scale (VAS) at 12, 24, 48, and 72 hours after treatment to assess pain levels. Analgesic intake is also recorded if applicable.
Pain assessments at 4 timepoints post-treatment (self-reported)
Trial Site Locations
Total: 1 location
1
Department of Operative Dentistry, HITEC-IMS Dental College
Rawalpindi, Punjab Province, Pakistan
Actively Recruiting
Research Team
M
Monal Fatima, BDS
B
Beenish Qureshi, BDS, FCPS
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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