Actively Recruiting
Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy
Led by Proton Collaborative Group · Updated on 2025-09-09
70
Participants Needed
4
Research Sites
2139 weeks
Total Duration
On this page
Sponsors
P
Proton Collaborative Group
Lead Sponsor
U
University of Florida Health
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to see what effects, good and/or bad, proton radiation, and/or conventional radiation and hormonal therapy (if applicable), has on prostate cancer that has already returned or the risk of prostate cancer returning.
CONDITIONS
Official Title
Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male patients treated for prostate cancer primarily with open, laparoscopic, or robotically assisted prostatectomy
- Maximum PSA value of 20 ng/ml
- Age 18 years or older
You will not qualify if you...
- Evidence of distant metastasis (M1)
- Prior systemic chemotherapy for any reason
- Previous pelvic irradiation that would prevent study treatment
- Active inflammatory bowel disease affecting the rectum (Crohn's disease, diverticulitis, or ulcerative colitis)
- History of hip replacement
- Prior or concurrent cancer other than non-melanomatous skin cancer unless disease free for at least 5 years
- Taking Saw Palmetto or methotrexate and unable or unwilling to stop during radiation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Proton Center of Arkansas
Little Rock, Arkansas, United States, 72205
Actively Recruiting
2
University of Florida Proton Therapy Institute
Jacksonville, Florida, United States, 32206
Actively Recruiting
3
Northwestern Medicine Chicago Proton Center
Warrenville, Illinois, United States, 60555
Actively Recruiting
4
Inova Schar Cancer Institute
Fairfax, Virginia, United States, 22031
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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