Comparison of Hemodynamic Management by Postural Mobilization Versus Chemical Vasoconstriction Using Noradrenaline Exclusively in Off-pump Coronary Artery Bypass Graft Surgery: A Prospective, Randomized, Comparative, Single-center Study.

What this Trial Is About

Researchers are evaluating two methods of managing blood flow during off-pump coronary artery bypass graft (CABG) surgery in adults with coronary artery disease. The study compares postural mobilization, specifically passive leg raising, with the use of noradrenaline alone. The goal is to determine how often noradrenaline is needed when using postural mobilization and to compare surgical outcomes and complications between the two groups. The study involves two groups: one where patients receive postural mobilization by raising their legs to about a 45° angle before any noradrenaline is given, and a control group where only noradrenaline is used to manage blood flow without leg raising. Postural mobilization is applied to help stabilize hemodynamics, and noradrenaline is used if needed. This intervention occurs during the heart surgery itself. Participants will be monitored during surgery and followed for 30 days afterward to assess how hemodynamics were managed, the rate of revascularization, and any post-operative complications. Researchers will measure the use of noradrenaline from the start to the end of surgery and observe patient outcomes during the follow-up period. The total participation includes the surgery day and 30 days post-surgery monitoring.

Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG Surgery