Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07163858

Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG Surgery

Led by Infirmerie Protestante de Lyon · Updated on 2025-12-03

50

Participants Needed

1

Research Sites

94 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This interventional prospective randomized study is designed to compare hemodynamic management using postural mobilization (+/- noradrenaline) versus noradrenaline only in patients undergoing open-heart coronary artery bypass graft (CABG) surgery.

CONDITIONS

Official Title

Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patient
  • Patient requiring isolated coronary bypass surgery
  • Elective procedure or medical emergency
  • First cardiac surgery
  • Patient with an EF �30%
  • Mandatory affiliation to a social security system
  • Signed informed consent form
  • Suspension of renin-angiotensin system inhibitors and angiontensn-neprilysin receptor blockers and sartans the day before surgical procedure
Not Eligible

You will not qualify if you...

  • Contraindication to an inotropic substance (only noradrenaline will be used)
  • Contraindication to passive leg raising
  • Patient in a life-threatening emergency
  • History of cardiac surgery
  • Bilateral iliac or common femoral artery occlusion
  • EF < 30%
  • Pregnancy and breastfeeding
  • Renal failure (GFR < 40 ml/min/1.73 m�b2)
  • Patient with bilateral thigh amputation
  • Class III obesity BMI > 40 kg/m�b2

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Infirmerie Protestante de Lyon

Caluire-et-Cuire, Auvergne-Rhône-Alpes, France, 69300

Actively Recruiting

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Research Team

S

SIESS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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