Actively Recruiting

Phase 1
Age: 21Years - 65Years
All Genders
NCT06070649

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Led by Yale University · Updated on 2026-04-28

63

Participants Needed

1

Research Sites

51 weeks

Total Duration

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Sponsors

Y

Yale University

Lead Sponsor

N

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This proposed study is a double-blind, randomized, placebo-controlled, parallel-group, laboratory study to determine the effects of DMT, plus psychotherapy, on Alcohol Use Disorder.

CONDITIONS

Official Title

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Who Can Participate

Age: 21Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of Alcohol Use Disorder by DSM-5 criteria
  • Medically healthy
  • Ability to provide consent
Not Eligible

You will not qualify if you...

  • Unstable medical conditions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Connecticut Mental Health Center

New Haven, Connecticut, United States, 06519

Actively Recruiting

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Research Team

A

Angelina Contreras

CONTACT

A

Ardavan Mohammad Aghaei

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

3

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