Actively Recruiting
POTS Adrenergic Ab (CIHR Aims #1&2)
Led by University of Calgary · Updated on 2026-05-05
125
Participants Needed
1
Research Sites
782 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Objective: In this pilot study, we will test the hypothesis that patients with POTS (age 18-60 years) will have a higher percentage of functional antibodies to adrenergic receptors compared with control subjects without POTS.
CONDITIONS
Official Title
POTS Adrenergic Ab (CIHR Aims #1&2)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients previously diagnosed with POTS
- Control subjects without a POTS diagnosis
- Age between 18 and 60 years
- Both males and females (aiming for similar female percentage as POTS patients)
- Able and willing to provide informed consent
You will not qualify if you...
- Current smokers
- Acute dehydration or other clear cause for postural tachycardia
- Significant cardiovascular, pulmonary, liver, or blood diseases
- Highly trained athletes
- Severe anxiety or somatization symptoms
- Use of drospirenone-containing oral contraceptives
- Hypertension defined as resting blood pressure over 145/95 mmHg off medications or requiring antihypertensive drugs
- Any condition or factor judged by investigators to prevent study completion, including poor compliance or unpredictable schedule
- Unable to give informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Calgary
Calgary, Alberta, Canada, T2N 4Z6
Actively Recruiting
Research Team
S
Satish R Raj, MD, MSCI
CONTACT
R
Robert S Sheldon, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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