Development of Powerly, unguided mobile app intervention preventing postpartum depression and anxiety & study protocol of randomized clinical trial.
Marta A Marciniak, Judith Rohde, Kenneth S L Yuen...
https://pubmed.ncbi.nlm.nih.gov/40607107/Actively Recruiting
Led by Marta Marciniak · Updated on 2025-05-20
140
Participants Needed
1
Research Sites
N/A
Total Duration
This research aims to evaluate if the Powerly app can help prevent postpartum depression and anxiety in healthy pregnant women. The study focuses on whether using the app reduces these mental health issues, improves emotion regulation, and enhances maternal bonding with the baby. Up to 30% of pregnant women experience high stress, with 15-20% facing postpartum depression and 25-35% experiencing anxiety, making this an important area for support. In this randomized study, 140 pregnant women between 24 and 32 weeks of pregnancy will be divided into two groups. One group will use the Powerly app daily for four weeks, which offers personalized psychological support based on cognitive behavioral therapy techniques. The other group will receive care as usual and gain access to the app after six weeks postpartum. Both groups will complete mental health assessments before starting, after four weeks, and six weeks after giving birth. Participants will complete questionnaires at these three time points to track symptoms of depression, anxiety, stress, emotion regulation, resilience, birth satisfaction, and maternal bonding. The study will also monitor app adherence during the four-week use period. Safety and well-being will be assessed through these measures, with total participation lasting until six weeks postpartum.
CONDITIONS
Powerly - Science-based Digital Intervention Preventing Postpartum Depression and Anxiety
M
Marta A. Marciniak, PhD
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Marta Marciniak
Lead Sponsor
University of Zurich
Collaborating Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person or remote) for eligibility assessment
Duration - 4 weeks
Participants in the intervention group use the Powerly app daily for 4 weeks to support mental well-being during pregnancy. Participants in the care as usual group continue their routine care without the app during this period.
1 baseline visit and 1 follow-up visit after 4 weeks
Duration - 6 weeks postpartum
Participants complete final questionnaires 6 weeks after giving birth to assess postpartum mental health outcomes.
1 visit (remote or in-person) at 6 weeks postpartum
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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Marta A Marciniak, Judith Rohde, Kenneth S L Yuen...
https://pubmed.ncbi.nlm.nih.gov/40607107/Marta Marciniak
Lead Sponsor
University of Zurich
Collaborating Sponsor