Actively Recruiting

Phase Not Applicable
Age: 18Years - 90Years
All Genders
NCT05274854

A Practice Change for Patients With Severe Chronic, Clinically Unexplained Gastrointestinal Symptoms

Led by The University of Queensland · Updated on 2024-11-12

200

Participants Needed

1

Research Sites

139 weeks

Total Duration

On this page

Sponsors

T

The University of Queensland

Lead Sponsor

P

Princess Alexandra Hospital, Brisbane, Australia

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research project aims to test whether early interventions delivered remotely and prior to integrated care clinic appointments are effective. Patients with chronic unexplained gastrointestinal symptoms will initially undergo structured assessment of symptoms and wheat intolerance delivered remotely. Patients who continue to experience symptoms will then be randomised to a pre-consultation intervention ((a) standardised dietician supervised intervention, b) exercise intervention, c) internet delivered cognitive behavior therapy or d) nothing) followed by randomisation to the consultation intervention ((a) consultant-led outpatient clinic or b) a integrated care clinic depending on their response to the initial intervention.

CONDITIONS

Official Title

A Practice Change for Patients With Severe Chronic, Clinically Unexplained Gastrointestinal Symptoms

Who Can Participate

Age: 18Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with relevant, chronic, or relapsing gastrointestinal symptoms without concerning features and on the wait list for integrated care clinic
  • Patients with severe symptoms as defined by a total Structured Assessment of Gastrointestinal Symptoms (SAGIS) score > 35
  • Patients aged 18 years or older to 90 years old
Not Eligible

You will not qualify if you...

  • Patients with alarm signs or symptoms like unexplained weight loss, gastrointestinal bleeding, iron deficiency anemia, or new onset gastrointestinal symptoms
  • Patients with mild or moderate symptoms not requiring clinical work-up or likely to improve on their own
  • Patients with comorbidities that interfere with the study interventions
  • Patients with a prior history of eating disorders, those wait listed for bariatric surgery, or those who have had bariatric surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Princess Alexandra Hospital

Woolloongabba, Queensland, Australia, 4102

Actively Recruiting

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Research Team

G

Gerald Holtmann, MD, PhD

CONTACT

N

Natasha Koloski, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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