Actively Recruiting
Praegnant Breast Cancer: Early/Advanced/Metastatic
Led by University Hospital Tuebingen · Updated on 2026-01-30
13500
Participants Needed
61
Research Sites
839 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Among patients with breast cancer the subgroup of patients with metastases are considered the group of patients with the worst prognosis. Not only regard-ing therapy decisions but also with regard to quality assured healthcare and health economics this entity of patients remains a challenge. Recently, novel advances in breast cancer therapy aim at the targeted therapy of tumor entities and identification of patients, for whom the greatest therapy benefit, and the least side effects are expected. However molecular assessment of the patient and the tumor in the metastatic situation is not performed on a routine basis and in many cases tumor character-istics from the primary tumor are considered reliable enough to make therapy decisions for the metastatic patients. Although molecular reassessment of tu-mor characteristics from tumor material of the metastasis is recommended in national guidelines, only a minority of patients is biopsied, because of the inva-siveness of the procedure, even though biopsy related complications are reported to be rare. With modern analytic methods from blood based biomaterial there seems to be an opportunity to correlate blood based tumor assessments with actual charac-teristics of the tumor. These include expression analysis, tumor mutation analy-sis, tumor gene copy number aberrations and others. One of the main aims of the PRAEGNANT study is therefore to establish an infrastructure for the compre-hensive analysis of tumor and metastatic molecular characteristics of the patient and the tumor. Furthermore, health care related outcomes as well as health economics provide novel approaches for integration of patients in study conduct and health care awareness and are study aims of the PRAEGNANT study.
CONDITIONS
Official Title
Praegnant Breast Cancer: Early/Advanced/Metastatic
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult breast cancer patients aged 18 years or older
- Patients with early breast cancer diagnosed within 91 days before study entry without distant metastases
- Adult women aged 18 years or older with invasive breast cancer
- Patients with metastatic or locally advanced, inoperable breast cancer confirmed by clinical measures
- Patients able and willing to sign the informed consent form
You will not qualify if you...
- Patients who have not signed the informed consent form
- Patients not eligible for observation due to non-availability or severe comorbidities as assessed by the treating physician
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 61 locations
1
Klinikum Sindelfingen-Böblingen gGmbH
Böblingen, Baden-Wurttemberg, Germany, 71032
Actively Recruiting
2
Klinik für Frauenheilkunde, Universitätsklinikum Freiburg
Freiburg im Breisgau, Baden-Wurttemberg, Germany, 79106
Actively Recruiting
3
NCT Heidelberg
Heidelberg, Baden-Wurttemberg, Germany, 69120
Actively Recruiting
4
ViDia Christliche Kliniken Karlsruhe
Karlsruhe, Baden-Wurttemberg, Germany, 76135
Actively Recruiting
5
Praxisklinik am Rosengarten
Mannheim, Baden-Wurttemberg, Germany, 68165
Actively Recruiting
6
medius Klinik Nürtingen
Nürtingen, Baden-Wurttemberg, Germany, 72622
Actively Recruiting
7
Universitätsfrauenklinik Tübingen
Tübingen, Baden-Wurttemberg, Germany
Actively Recruiting
8
Universitätsfrauenklinik Ulm
Ulm, Baden-Wurttemberg, Germany, 89081
Actively Recruiting
9
Gesundheitszentrum St. Marien GmbH
Amberg, Bavaria, Germany, 92224
Actively Recruiting
10
Anregiomed gKK Klinikum Ansbach Brustzentrum Westmittelfranken
Ansbach, Bavaria, Germany, 91522
Actively Recruiting
11
Hämatologische-onkologische Praxis
Augsburg, Bavaria, Germany, 86150
Completed
12
Klinikum Augsburg
Augsburg, Bavaria, Germany, 86156
Actively Recruiting
13
Sozialstiftung Bamberg Klinikum am Bruderwald
Bamberg, Bavaria, Germany, 96049
Actively Recruiting
14
Klinikum Bayreuth
Bayreuth, Bavaria, Germany, 95445
Actively Recruiting
15
DONAUISAR Klinikum
Deggendorf, Bavaria, Germany, 94469
Actively Recruiting
16
Onkologisches Zentrum Donauwörth
Donauwörth, Bavaria, Germany, 86609
Actively Recruiting
17
Rottal-Inn-Kliniken GmbH
Eggenfelden, Bavaria, Germany, 84307
Actively Recruiting
18
Universitätsfrauenklinik Erlangen
Erlangen, Bavaria, Germany, 91012
Actively Recruiting
19
Klinikum Fürth
Fürth, Bavaria, Germany, 90766
Actively Recruiting
20
MVZ am Klinikum Aschaffenburg - Zweigpraxis für Hämatologie und Onkologie
Hösbach, Bavaria, Germany, 63768
Actively Recruiting
21
Onkologie Elisenhof, München
München, Bavaria, Germany, 80335
Completed
22
Klinikum der Universität München Frauenklinik
München, Bavaria, Germany, 81337
Actively Recruiting
23
Frauenklinik und Poliklinik der Technischen Universität München
München, Bavaria, Germany, 81675
Actively Recruiting
24
Caritas-Krankenhaus St. Josef
Regensburg, Bavaria, Germany, 93053
Actively Recruiting
25
Universitätsklinikum Würzburg
Würzburg, Bavaria, Germany, 97080
Actively Recruiting
26
Praxis für Frauenheilkunde und Geburtshilfe
Fürstenwalde, Brandenburg, Germany, 015517
Actively Recruiting
27
Ruppiner Kliniken GmbH, Hochschulklinikum der Med. Hochschule Brandenburg
Neuruppin, Brandenburg, Germany, 16816
Actively Recruiting
28
Immanuel Klinik und Poliklinik Rüdersdorf GmbH
Rüdersdorf, Brandenburg, Germany, 15562
Actively Recruiting
29
Universitätsklinikum Hamburg-Eppendorf
Hamburg, Free and Hanseatic City of Hamburg, Germany, 20246
Actively Recruiting
30
Onkologie Lerchenfeld
Hamburg, Free and Hanseatic City of Hamburg, Germany, 22081
Completed
31
Klinikum Darmstadt Frauenklinik
Darmstadt, Hesse, Germany, 64283
Actively Recruiting
32
Centrum für Hämatologie und Onkologie Bethanien
Frankfurt am Main, Hesse, Germany, 60389
Actively Recruiting
33
Klinikum Kassel GmbH
Kassel, Hesse, Germany, 34125
Actively Recruiting
34
Gemeinschaftspraxis für Hämatologie und Onkologie
Langen, Hesse, Germany, 63225
Actively Recruiting
35
Lahn-Dill-Kliniken GmbH Klinikum Wetzlar
Wetzlar, Hesse, Germany, 35578
Completed
36
Niels-Stensen-Kliniken
Georgsmarienhütte, Lower Saxony, Germany, 49124
Actively Recruiting
37
Onkologische Schwerpunktpraxis Leer-Emden
Leer, Lower Saxony, Germany, 26789
Actively Recruiting
38
g.SUND Gynäkologie Kompetenzzentrum Stralsund
Stralsund, Mecklenburg-Vorpommern, Germany, 18435
Actively Recruiting
39
Uniklinik RWTH Aachen
Aachen, North Rhine-Westphalia, Germany, 52074
Actively Recruiting
40
Gynäkologie und Geburtshilfe im medizinischen Zentrum Bonn
Bonn, North Rhine-Westphalia, Germany, 53111
Actively Recruiting
41
Marienhospital
Bottrop, North Rhine-Westphalia, Germany, 46236
Actively Recruiting
42
Universitätsfrauenklinik Düsseldorf
Düsseldorf, North Rhine-Westphalia, Germany, 40225
Actively Recruiting
43
Kliniken Essen-Mitte
Essen, North Rhine-Westphalia, Germany, 45136
Completed
44
Herne, North Rhine-Westphalia, Germany, 44623
Completed
45
Institut für Versorgungsforschung in der Onkologie GbR
Koblenz, North Rhine-Westphalia, Germany, 56068
Actively Recruiting
46
St. Vincenz-Krankenhaus GmbH
Paderborn, North Rhine-Westphalia, Germany, 33098
Actively Recruiting
47
Praxis Onkologie und Hämatologie
Recklinghausen, North Rhine-Westphalia, Germany, 45657
Completed
48
Gesellschaft für Medizinische Studien Würselen
Würselen, North Rhine-Westphalia, Germany, 52146
Actively Recruiting
49
Schwerpunktpraxis für Hämatologie und Onkologie
Kaiserslautern, Rhineland-Palatinate, Germany, 67655
Actively Recruiting
50
Institut für Versorgungsforschung
Mayen, Rhineland-Palatinate, Germany, 56727
Actively Recruiting
51
Klinikum Chemnitz gGmbH
Chemnitz, Saxony, Germany, 09116
Actively Recruiting
52
Universitätsklinik Dresden
Dresden, Saxony, Germany, 01307
Actively Recruiting
53
Universitäres Krebszentrum Leipzig
Leipzig, Saxony, Germany, 04103
Actively Recruiting
54
Kreiskrankenhaus Torgau
Torgau, Saxony, Germany, 04860
Actively Recruiting
55
Universitätsklinikum Halle (Saale)
Halle, Saxony-Anhalt, Germany, 06120
Actively Recruiting
56
Klinik für Gynäkologie und Geburtshilfe
Kiel, Schleswig-Holstein, Germany, 24105
Completed
57
Universitätsklinikum Schleswig-Holstein
Lübeck, Schleswig-Holstein, Germany, 23538
Actively Recruiting
58
Charité
Berlin, State of Berlin, Germany, 10117
Completed
59
MediOnko-Institut GbR
Berlin, State of Berlin, Germany, 10367
Actively Recruiting
60
Klinik für Gynäkologie und Geburtshilfe, Helios Kliniken
Berlin, State of Berlin, Germany, 13125
Actively Recruiting
61
medius KLINIKEN gGmbH, medius KLINIK Ostfildern-Ruit
Ostfildern, Germany, 73760
Actively Recruiting
Research Team
E
Erik Belleville, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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