Actively Recruiting

Age: 50Years +
FEMALE
NCT05836844

Pragmatic Evaluation of Performance and Safety of the Anchorsure® Transvaginal Device for Surgical Treatment of Apical Prolapse in Women

Led by Centre Hospitalier Universitaire de Nīmes · Updated on 2025-11-17

120

Participants Needed

4

Research Sites

264 weeks

Total Duration

On this page

Sponsors

C

Centre Hospitalier Universitaire de Nīmes

Lead Sponsor

U

University Hospital, Lille

Collaborating Sponsor

AI-Summary

What this Trial Is About

Pelvic Organ Prolapse affects 50% of parous women, and apical prolapse is one of the most common types of prolapse. Treatment for apical prolapse ranges from observation, non-surgical treatment or surgical repair. An anchoring device can reduce dissection and operative time and is meant to provide strong fixation whilst minimizing potential postoperative pain by avoiding neurovascular injuries. These potential advantages must be evaluated in terms of performance and safety. This cohort study will be on patients undergoing sacrospinous fixation with the Anchorsure® system with a follow-up of 36 months.

CONDITIONS

Official Title

Pragmatic Evaluation of Performance and Safety of the Anchorsure® Transvaginal Device for Surgical Treatment of Apical Prolapse in Women

Who Can Participate

Age: 50Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women with pelvic organ prolapse with leading edge at or beyond the hymen confirmed by pelvic organ prolapse quantification system (POP-Q)
  • Women scheduled for apical prolapse surgery using the Anchorsure System® with or without native tissue repair, hysterectomy, or sling for stress urinary incontinence
  • Women who have not objected to participating in the study
  • Women who have been properly informed about the study
Not Eligible

You will not qualify if you...

  • Participation in another device or drug interventional study within the last three months (except VIGI-MESH national registry)
  • Patients scheduled for prolapse repair without apical suspension or with other than native tissue repair and Anchorsure System®
  • Patients with uncontrolled diabetes mellitus
  • Patients with active uncontrolled or chronic gynecologic or urinary tract infections or local tissue necrosis
  • Patients with ongoing pelvic organ cancer
  • Patients with history of pelvic area radiotherapy
  • Patients on immunosuppressive or immunomodulatory treatment within the previous month
  • Patients under ongoing oral anticoagulant therapy
  • Patients with stage 0 or 1 pelvic organ prolapse at the time of surgery
  • Patients with preoperative infection contraindicating surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

La Rochelle General Hospital

La Rochelle, France, 17000

Actively Recruiting

2

Lille University Hospital

Lille, France, 59000

Actively Recruiting

3

Kremlin-Bicêtre Hospital

Paris, France, 94270

Actively Recruiting

4

Clinique Sainte-Anne

Strasbourg, France, 67000

Actively Recruiting

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Research Team

R

Renaud de TAYRAC, Professor

CONTACT

A

Anissa MEGZARI

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Pragmatic Evaluation of Performance and Safety of the Anchorsure® Transvaginal Device for Surgical Treatment of Apical Prolapse in Women | DecenTrialz