Study of Pre-emptive Endoscopic Vacuum Therapy to Prevent Anastomotic Leakage After Colorectal Cancer Surgery

What this Trial Is About

Researchers are evaluating the safety and effectiveness of postoperative Pre-emptive Endoscopic Vacuum Therapy PEVT in reducing anastomotic leaks within 30 days after colorectal cancer surgery. The study compares patients receiving PEVT with those receiving standard care without PEVT, focusing on differences in operation time, hospital stay length, medical costs, and other postoperative complications like wound infection, abdominal abscess, and intestinal obstruction. The study involves two groups one group receives PEVT immediately after confirming the anastomosis is intact via endoscopy, where a specialized sponge device is placed at the surgical site to provide continuous low-intensity suction. The other group receives routine colonoscopy without the PEVT device, with all other procedures being the same. The therapy is applied shortly after surgery and monitored for related adverse events such as device displacement, bleeding, and infection. Participants will be closely monitored through various assessments including postoperative recovery indicators like time to first flatus, first defecation, and ambulation. Researchers will track the presence of anastomotic leaks and other complications within 30 days after surgery. The study will also measure operation time, length of hospital stay, total medical costs, and any PEVT-related side effects. The total participation period includes the initial surgery and a 30-day follow-up.

Pre-emptive Endoscopic Vacuum Therapy Reduces the Incidence of Anastomotic Leakage After Colorectal Cancer Surgery