Home-Based Preoperative Exercise and Mindfulness Program for Adults Undergoing Radical Cystectomy for Bladder Cancer

What this Trial Is About

Researchers are studying a program combining mindfulness and exercise before surgery for patients with bladder cancer who are scheduled to have their bladder removed radical cystectomy. This pilot trial aims to see if it is feasible to use a home-based pre-operative exercise and mindfulness program to improve patients physical and psychological health before surgery. The study is led by the University of Virginia and focuses on patients with muscle-invasive or high-risk non-muscle-invasive bladder cancer. Participants are randomly assigned to either usual preoperative care or a prehabilitation program that includes two main parts a virtual, twice-weekly cycling exercise guided by an instructor using a special exercise bike and wristband tracker, and daily self-directed mindfulness meditation using guided imagery audio on a wristband tracker. Both parts last for 30 days before surgery, with participants logging their exercise and meditation days. During the study, researchers will track how many days participants spend exercising and engaging in solitary psychological support over 30 days. They will also assess post-operative complications within 30 days after surgery and measure quality of life, peak oxygen uptake, mindfulness, and stress levels before and after surgery using questionnaires and exercise testing. Participants must be able to use the study devices and complete the exercise safely. The study period includes pre-operative monitoring and follow-up assessments up to 30 days after surgery.

Pre-Habilitation with Mindfulness and Exercise for Patients Undergoing Radical Cystectomy (PRIMER Trial)