Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07182773

Pre-infusion Aerobic Cycling Exercise for CardioRespiratory Fitness in Cancer Patients

Led by University of Dublin, Trinity College · Updated on 2026-05-04

80

Participants Needed

1

Research Sites

101 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Background to this Research Patients who undergo cancer treatment involving chemotherapy or immunotherapy, can experience considerable reductions in their fitness levels. This is a concern, as exercise is a really important part of cancer care. Therefore delivering exercise programmes that support patients during their chemotherapy or immunotherapy treatment will be essential to helping people to maintain their fitness levels. Research is needed to examine the best way to introduce exercise into the patient pathway in a way that is convenient and patient-centred. The Specific Questions Being Asked This research project aims to examine the effect of an exercise programme which involves exercising on the cancer treatment day ward with a physiotherapist while waiting for treatment infusion as a safe and effective way of supporting patients to keep fit and active during chemotherapy treatment. The trial will also investigate if it the prescribed moderate intensity exercise for 30 minutes is manageable for patients. Trial Plan This project will be delivered as a randomised controlled trial. All participants enrolled on the trial will receive information and advice about physical activity during chemotherapy treatment from a physiotherapist with expertise in cancer care. The intervention arm will also complete an exercise session with the physiotherapist on the day of their infusion treatment over a period of 12 weeks. The feasibility of this protocol has already been tested in 17 participants with very positive results. The information gained from this initial study will be used to deliver this trial, which will recruit 80 participants. It is hoped that the information gained from this research will provide a practical way of providing supervised exercise training for patients during chemotherapy or immunotherapy that is safe, expert-led and patient centred.

CONDITIONS

Official Title

Pre-infusion Aerobic Cycling Exercise for CardioRespiratory Fitness in Cancer Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged over 18 years
  • Histological confirmed diagnosis of stage I to IIIc breast, ovarian, or colorectal cancer
  • Scheduled to receive chemotherapy with or without immunotherapy with curative intent for at least 12 weeks
  • Medical clearance from oncologist to participate in regular exercise according to ACSM preparticipation screening
  • Ability to use an exercise bike independently
  • Ability to provide written informed consent
Not Eligible

You will not qualify if you...

  • Advanced or metastatic disease
  • Scheduled to receive concurrent chemoradiotherapy
  • New or existing pain preventing use of the exercise bike
  • Inability to read and understand English
  • Deemed unfit after cardiopulmonary exercise testing (CPET)
  • Unstable angina, arrhythmia, hypertension, or decompensated heart failure
  • Dementia or psychiatric illness preventing safe independent exercise
  • Acute untreated embolus or infarct
  • Dissecting aneurysm
  • Acute myocarditis or pericarditis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Beacon Hospital Dublin

Dublin, Ireland

Actively Recruiting

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Research Team

A

Aoife McGovern

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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