Actively Recruiting

Phase Not Applicable
Age: 18Years - 100Years
All Genders
NCT05381818

Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery

Led by University of Florida · Updated on 2025-08-29

36

Participants Needed

1

Research Sites

213 weeks

Total Duration

On this page

Sponsors

U

University of Florida

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this research study is to evaluate effects of respiratory strengthening exercises on breathing function, in people who have orthopedic surgery. It is known that breathing function decreases for a few days after surgery. in In this study, we want to see if exercising before surgery strengthens the breathing muscles and improves recovery after surgery.

CONDITIONS

Official Title

Pre-operative Inspiratory Muscle Strength Training in Total Joint Surgery

Who Can Participate

Age: 18Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older
  • History of current or previous tobacco use, including vaping with nicotine
  • At least one risk factor for post-operative pulmonary complications such as diagnosed lung disease, shortness of breath with minimal exertion, FEV1 or FVC less than 80% predicted, or respiratory muscle strength below normal for age and sex
  • History of smoking-related lung disease
  • Scheduled surgery expected to last more than 30 minutes
  • Ability to follow instructions for inspiratory muscle training exercises
  • Ability to communicate pain, fatigue, or need for assistance
Not Eligible

You will not qualify if you...

  • American Society of Anesthesiologists physical status classification of 4 or higher
  • Recent acute pneumonia or lower respiratory infection within the past 2 weeks requiring corticosteroids or antibiotics
  • Dependence on continuous supplemental oxygen before surgery
  • Dependence on positive pressure breathing support while awake and upright (nighttime CPAP allowed)
  • Diagnosis of neurological conditions such as MS, ALS, Parkinson's disease, or stroke
  • Participation in a pulmonary rehabilitation program
  • Severe obstructive pulmonary disease classified as GOLD 3 or higher (FEV1 less than 50% predicted)
  • Presence of infectious disease requiring isolation, such as COVID-19

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Florida

Jacksonville, Florida, United States, 32209

Actively Recruiting

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Research Team

M

Maribel Z Ciampitti

CONTACT

T

Tatiana Elias-Grajeda

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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