Actively Recruiting
Pre-Surgical Immunonutrition's Effect on Colorectal Surgery
Led by Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran · Updated on 2026-03-27
126
Participants Needed
1
Research Sites
188 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Colorectal surgery patients face excessive catabolism, increasing inflammation and immune compromise. The administration of nutritional supplements known as immunonutrition before gastrointestinal surgery has been shown to improve clinical outcomes; however, the mechanisms underlying these benefits remain inconclusive. The objective of the study is to evaluate the effect of preoperative nutritional supplementation with an immunonutrient-enriched formula compared to an isocaloric and isoproteic formula on plasma BCAA concentration in patients undergoing elective colorectal surgery. A double-blind, randomized controlled clinical trial will be conducted. Patients will be required to drink the supplement daily for the 7 days preceding the surgical intervention. Patients in both groups will be instructed to maintain their usual food intake. During the study, there will be two patient assessments and a review of medical records to document the outcomes.
CONDITIONS
Official Title
Pre-Surgical Immunonutrition's Effect on Colorectal Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Both sexes
- Over 18 years of age
- Scheduled for elective colorectal surgery involving resection and intestinal reconnection
- Able and willing to provide informed consent
You will not qualify if you...
- Use of nutritional supplements within 2 weeks before enrollment
- Use of additional nutritional supplements during the 7-day study intervention
- Diagnosis of chronic kidney disease
- Diagnosis of hepatic cirrhosis
- Allergy to any ingredients in the study formulas, including milk or soy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Aurora E Serralde Zúñiga, MD, PhD
Mexico City, Tlalpan, Mexico, 14080
Actively Recruiting
Research Team
A
Aurora E Serralde Zúñiga, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here