Actively Recruiting
The PRE-VAIL Study
Led by The First Hospital of Jilin University · Updated on 2026-02-09
259
Participants Needed
1
Research Sites
127 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
During the prone position, there may be an increase in intragastric pressure. The investigators focus on a scientific question: Whether reducing enteral nutrition before the prone position will benefit patients with severe mechanically ventilated acute respiratory distress syndrome (ARDS). The experimental group had the enteral nutrition dose reduced before the prone position, while the control group did not have the enteral nutrition dose reduced
CONDITIONS
Official Title
The PRE-VAIL Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Within 24 hours of ICU admission, failure of one or more organ systems with a SOFA score of 2 or higher
- Diagnosis of moderate or severe ARDS with oxygenation index less than 150 mmHg and PEEP of 5 cm H2O or more despite optimized ventilation
- Expected ICU stay longer than 48 hours
You will not qualify if you...
- Contraindications to prone positioning
- Contraindications to enteral nutrition preventing early feeding within 48 hours
- Expected to die within 48 hours
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The First Hospital of Jilin University
Changchun, Jilin, China, 130021
Actively Recruiting
Research Team
Y
Youquan Wang, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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